Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AADAT | Q8N5Z0 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GOT1 | P17174 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.33 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853909 | 1.00 | LMNA (0.36) | LMNAKDM4EBRD4CYP19A1ALDH1A1 | |
| Bromide SCHEMBL20548193 | 0.98 | LMNA (0.35) | LMNAKDM4EBRD4CYP19A1ALDH1A1 | |
| SCHEMBL18471609 | 0.82 | CYP19A1 (0.36) | CYP19A1ALDH1A1SMN1; SMN2HTTTP53 | |
| SCHEMBL14275616 | 0.80 | CYP19A1 (0.53) | CYP19A1ALDH1A1SMN1; SMN2HTTTP53 | |
| SCHEMBL21450546 | 0.78 | CYP19A1 (0.35) | BRD4CYP19A1ALDH1A1HTTTP53 | |
| SCHEMBL22815230 | 0.76 | ADAM17 (0.36) | LMNAKDM4EBRD4CYP19A1SMN1; SMN2 | |
| SCHEMBL13071576 | 0.76 | BRD4 (0.39) | LMNAKDM4EBRD4CYP19A1ALDH1A1 | |
| SCHEMBL24624701 | 0.76 | CYP19A1 (0.36) | CYP19A1ALDH1A1SMN1; SMN2HTTTP53 | |
| SCHEMBL2687595 | 0.76 | GAA (0.38) | LMNACYP19A1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL2848946 | 0.76 | GAA (0.38) | LMNACYP19A1ALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144768-A1 | KINASE INHIBITOR COMPOUNDS | COMPASS HORIZON FUNDING COMPANY LLC | 2010-06-10 | — | — | US | claimed |
| EP-2166857-A1 | KINASE INHIBITOR COMPOUNDS | Xcovery, INC. (US) | 2010-03-31 | — | — | EP | claimed |
| WO-2008153942-A1 | KINASE INHIBITOR COMPOUNDS | XCOVERY, INC. (US) | 2008-12-18 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144768-A1 | KINASE INHIBITOR COMPOUNDS | MAP3K9, MAP3K1, MAP3K8 | LMNA 3361/4885KDM4E 1198/4885BRD4 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.