SCHEMBL246263

SCHEMBL246263

COCC(=O)c1ccc(OC)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.66
HDAC4 P56524 2/20 0.66
HDAC1 Q13547 2/20 0.66
HDAC7 Q8WUI4 2/20 0.66
HDAC2 Q92769 2/20 0.66
HDAC10 Q969S8 2/20 0.66
HDAC11 Q96DB2 2/20 0.66
HDAC8 Q9BY41 2/20 0.66
HDAC6 Q9UBN7 2/20 0.66
HDAC9 Q9UKV0 2/20 0.66
HDAC5 Q9UQL6 2/20 0.66
GSK3B P49841 1/20 0.66
ESR2 Q92731 1/20 0.62
LMNA P02545 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
MAPT P10636 2/20 0.59
CES2 O00748 1/20 0.59
CES1 P23141 1/20 0.59
PDE4B Q07343 1/20 0.58
CA1 P00915 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11323924 0.88 HDAC3 (0.66) HDAC3HDAC4HDAC1HDAC7HDAC2
Anisole SCHEMBL4124697 0.86 L3MBTL1 (0.57) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL21100591 0.86 MAPT (0.73) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL16552644 0.83 MMP1 (0.76) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL153386 0.83 ALDH1A1 (0.76) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL16202989 0.82 ELANE (0.55) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL28691916 0.82 HDAC3 (0.59) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL3042221 0.82 ALDH1A1 (0.70) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL773971 0.81 HDAC3 (0.58) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL773970 0.81 HDAC3 (0.58) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116924993-A Preparation method of 1-cyclopentyl-3- (2, 4-dimethoxy phenyl) -2-oxo ethyl) imidazolidine-2, 4, 5-trione 川北医学院 2023-10-24 CN claimed
CN-115960480-B Light response self-repairing material containing thymine derivative and application thereof 合肥工业大学 2023-09-12 CN claimed
CN-115960480-A Light response self-repairing material containing thymine derivative and application thereof 合肥工业大学 2023-04-14 CN claimed
CN-114146071-B Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2023-02-28 CN claimed
CN-114146071-A Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2022-03-08 CN claimed
CN-112778208-A Dihydropyrazole MurA enzyme inhibitor molecule and preparation method and application thereof 中南民族大学 2021-05-11 CN claimed
CN-108484511-A A kind of ligustrazine chalcone compounds and its preparation method and application 山东大学 2018-09-04 CN claimed
EP-2906529-B9 A NEW PRODUCTION METHOD AND NEW INTERMEDIATES OF SYNTHESIS OF ELVITEGRAVIR ZENTIVA KS (CZ) 2017-03-15 EP claimed
EP-2906529-B1 A NEW PRODUCTION METHOD AND NEW INTERMEDIATES OF SYNTHESIS OF ELVITEGRAVIR ZENTIVA KS (CZ) 2016-11-23 EP claimed
CN-105907342-A Silicone sealant for aluminum-sheet curtain wall 烟台图文马克化工科技有限公司 2016-08-31 CN claimed
CN-105237037-A Water-proofing agent for natural stone building YANTAI SHUNLONG CHEMICAL ENGINEERING TECHNOLOGY CO LTD 2016-01-13 CN claimed
EP-2906529-A1 A NEW PRODUCTION METHOD AND NEW INTERMEDIATES OF SYNTHESIS OF ELVITEGRAVIR Zentiva K.S. (CZ) 2015-08-19 EP claimed
CN-104447556-A Compound with analgesic effect and preparation method thereof UNIV SOUTH CENTRAL NATIONALITI 2015-03-25 CN claimed
CN-103030647-B Method for synthesizing glabridin SHANDONG ANALYSIS TEST CENTER (CN) 2014-10-29 CN claimed
WO-2014056464-A1 A NEW PRODUCTION METHOD AND NEW INTERMEDIATES OF SYNTHESIS OF ELVITEGRAVIR ZENTIVA, K.S. (CZ) 2014-04-17 WO claimed
CN-103030647-A Method for synthesizing glabridin SHANDONG ANALYSIS & TEST CT 2013-04-10 CN claimed
EP-1349823-B1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR CHEMTURA CORP (US) 2007-11-21 EP claimed
EP-1349823-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR Crompton Corporation (US) 2003-10-08 EP claimed
WO-2002055466-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR CROMPTON CORPORATION (US) 2002-07-18 WO claimed
US-6410795-B1 FORMING DIKETONES CROMPTON CORPORATION 2002-06-25 US claimed