Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10027698 | 0.79 | ALDH1A1 (0.59) | KDM4EALDH1A1ADORA2AADORA1LMNA | |
| SCHEMBL405843 | 0.79 | ALDH1A1 (0.59) | KDM4EALDH1A1ADORA2AADORA1LMNA | |
| SCHEMBL2715150 | 0.79 | GRM5 (0.46) | KDM4EALDH1A1ADORA2AADORA1LMNA | |
| SCHEMBL1489646 | 0.77 | ADORA2A (0.55) | KDM4EALDH1A1ADORA2AADORA1LMNA | |
| SCHEMBL14955783 | 0.77 | NOTUM (0.48) | KDM4EALDH1A1ADORA2AADORA1LMNA | |
| SCHEMBL23190294 | 0.76 | SMN1; SMN2 (0.47) | KDM4EALDH1A1ADORA2AADORA1MAPT | |
| SCHEMBL20416864 | 0.76 | KDM4E (0.46) | KDM4EALDH1A1ADORA2AADORA1LMNA | |
| SCHEMBL14009584 | 0.76 | ADORA2A (0.54) | KDM4EALDH1A1ADORA2AADORA1LMNA | |
| SCHEMBL26892481 | 0.76 | ADORA2A (0.54) | KDM4EALDH1A1ADORA2AADORA1LMNA | |
| SCHEMBL199306 | 0.76 | ALDH1A1 (0.65) | KDM4EALDH1A1ADORA2AADORA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2053049-B1 | Preparation of 2' , 6' -di-pyrazolyl-pyridine containing a reactive group R in 4' position | KARLSRUHER INST TECHNOLOGIE (DE) | 2011-09-21 | — | — | EP | disclosed |
| EP-2053049-B1 | Preparation of 2' , 6' -di-pyrazolyl-pyridine containing a reactive group R in 4' position | KARLSRUHER INST TECHNOLOGIE (DE) | 2011-09-21 | — | — | EP | disclosed |
| EP-2053049-A1 | Preparation of 2' , 6' -di-pyrazolyl-pyridine containing a reactive group R in 4' position | Forschungszentrum Karlsruhe GmbH (DE) | 2009-04-29 | — | — | EP | disclosed |
| EP-2053049-A1 | Preparation of 2' , 6' -di-pyrazolyl-pyridine containing a reactive group R in 4' position | Forschungszentrum Karlsruhe GmbH (DE) | 2009-04-29 | — | — | EP | disclosed |