SCHEMBL10027698

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15764343	0.82	CCR1 (0.52)	ALDH1A1KDM4EGRM5KMT2ANPC1
	SCHEMBL2462672	0.79	KDM4E (0.59)	ALDH1A1KDM4EGRM5MAPTLMNA
	SCHEMBL405843	0.79	ALDH1A1 (0.59)	ALDH1A1KDM4EGRM5MAPTLMNA
	SCHEMBL8008287	0.79	GRM5 (0.56)	ALDH1A1KDM4EGRM5LMNAKMT2A
	SCHEMBL14964128	0.77	MAPT (0.49)	ALDH1A1KDM4EGRM5MAPTLMNA
	SCHEMBL873113	0.77	MAPT (0.53)	ALDH1A1KDM4EGRM5MAPTLMNA
	SCHEMBL7078074	0.76	GRM5 (0.37)	ALDH1A1KDM4EGRM5MAPTLMNA
	SCHEMBL23190294	0.76	SMN1; SMN2 (0.47)	ALDH1A1KDM4EMAPTADORA2AADORA1
	SCHEMBL26892481	0.76	ADORA2A (0.54)	ALDH1A1KDM4EMAPTLMNAMEN1
	SCHEMBL199306	0.76	ALDH1A1 (0.65)	ALDH1A1KDM4EGRM5MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.