Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2462672 | 0.79 | KDM4E (0.59) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL10027698 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL199306 | 0.76 | ALDH1A1 (0.65) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL12532330 | 0.74 | KDM4E (1.00) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL28812535 | 0.74 | ALDH1A1 (0.63) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL31519065 | 0.74 | ALDH1A1 (0.63) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL31435409 | 0.73 | LMNA (0.59) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL28187273 | 0.71 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL4191891 | 0.71 | LMNA (0.57) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL9521570 | 0.70 | SMN1; SMN2 (0.67) | ALDH1A1KDM4ELMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120020886-A1 | THERMAL SPIN CROSS-OVER COMPOUNDS AND METHODS OF USING SAME | UNIVERSITY OF HYDERABAD (IN) | 2012-01-26 | — | — | US | disclosed |
| US-20120020886-A1 | THERMAL SPIN CROSS-OVER COMPOUNDS AND METHODS OF USING SAME | UNIVERSITY OF HYDERABAD (IN) | 2012-01-26 | — | — | US | disclosed |
| US-20120020886-A1 | THERMAL SPIN CROSS-OVER COMPOUNDS AND METHODS OF USING SAME | UNIVERSITY OF HYDERABAD (IN) | 2012-01-26 | — | — | US | disclosed |
| EP-2053049-A1 | Preparation of 2' , 6' -di-pyrazolyl-pyridine containing a reactive group R in 4' position | Forschungszentrum Karlsruhe GmbH (DE) | 2009-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120020886-A1 | THERMAL SPIN CROSS-OVER COMPOUNDS AND METHODS OF USING SAME | SLC10A1, SLC10A2, SPIN2B | ALDH1A1 1214/4885KDM4E 4782/4885LMNA 1281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.