SCHEMBL24628245

SCHEMBL24628245

c1ccc(-c2nc(-c3ccc(-c4ccc5c(c4)c4c(-c6ccccc6)ccc6oc7cccc5c7c64)cc3)nc(-c3ccc4ccccc4c3)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 3/20 0.38
HSD17B10 Q99714 3/20 0.38
CYP1A2 P05177 2/20 0.38
KMT2A Q03164 2/20 0.38
TP53 P04637 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MEN1 O00255 1/20 0.38
PGR P06401 1/20 0.36
PLA2G2A P14555 2/20 0.35
PLA2G4A P47712 2/20 0.35
CASP3 P42574 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
MAPT P10636 3/20 0.34
HSD17B1 P14061 2/20 0.34
HSD17B2 P37059 2/20 0.34
HPGD P15428 2/20 0.34
TSHR P16473 2/20 0.34
PLA2G10 O15496 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24628242 1.00 ALDH1A1 (0.38) ALDH1A1KDM4EHSD17B10CYP1A2KMT2A
SCHEMBL24628249 0.94 ALDH1A1 (0.42) ALDH1A1KDM4EHSD17B10CYP1A2KMT2A
SCHEMBL24628544 0.92 PLA2G2A (0.40) ALDH1A1KDM4EHSD17B10KMT2ATP53
SCHEMBL24628554 0.91 PLA2G2A (0.39) ALDH1A1KDM4EHSD17B10KMT2ATP53
SCHEMBL24628321 0.91 PLA2G2A (0.39) ALDH1A1KDM4EHSD17B10KMT2ATP53
SCHEMBL24628876 0.91 ALDH1A1 (0.36) ALDH1A1KDM4EHSD17B10CYP1A2KMT2A
SCHEMBL24628236 0.90 CYP1A2 (0.43) ALDH1A1KDM4EHSD17B10CYP1A2KMT2A
SCHEMBL24628815 0.88 MEN1 (0.38) ALDH1A1KDM4EKMT2AMEN1PLA2G2A
SCHEMBL24628243 0.87 CYP1A2 (0.40) ALDH1A1KDM4EHSD17B10CYP1A2KMT2A
SCHEMBL26271373 0.86 ALDH1A1 (0.41) ALDH1A1KDM4EHSD17B10CYP1A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022148717-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-07-14 WO disclosed