SCHEMBL24628554

SCHEMBL24628554

c1ccc(-c2ccc3c(c2)c2c(-c4cccc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)c4)ccc4oc5cccc3c5c42)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.39
PLA2G4A P47712 4/20 0.39
PLA2G10 O15496 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.35
GAA P10253 1/20 0.35
CASP3 P42574 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
PIM1 P11309 1/20 0.34
CSNK2A2 P19784 1/20 0.34
CSNK2B P67870 1/20 0.34
PIM3 Q86V86 1/20 0.34
PIM2 Q9P1W9 1/20 0.34
PGR P06401 1/20 0.33
HPSE Q9Y251 1/20 0.33
PRKDC P78527 1/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 3/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24628321 1.00 PLA2G2A (0.39) PLA2G2APLA2G4APLA2G10L3MBTL1GAA
SCHEMBL24628544 0.96 PLA2G2A (0.40) PLA2G2APLA2G4APLA2G10L3MBTL1GAA
SCHEMBL24628524 0.93 KMT2A (0.38) PLA2G2APLA2G4APLA2G10L3MBTL1GAA
SCHEMBL24628548 0.92 MAPT (0.36) PLA2G2APLA2G4APLA2G10L3MBTL1ALDH1A1
SCHEMBL24628815 0.92 MEN1 (0.38) PLA2G2APLA2G4APLA2G10L3MBTL1GAA
SCHEMBL24628245 0.91 ALDH1A1 (0.38) PLA2G2APLA2G4APLA2G10L3MBTL1GAA
SCHEMBL24628242 0.91 ALDH1A1 (0.38) PLA2G2APLA2G4APLA2G10L3MBTL1GAA
SCHEMBL24628571 0.87 PLA2G2A (0.43) PLA2G2APLA2G4APLA2G10L3MBTL1GAA
SCHEMBL24628082 0.87 PLA2G2A (0.43) PLA2G2APLA2G4APLA2G10L3MBTL1GAA
SCHEMBL24628541 0.87 PLA2G2A (0.43) PLA2G2APLA2G4APLA2G10L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022148717-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-07-14 WO disclosed