Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | PNMT | P11086 | 5/20 | 0.39 |
| ▸ | CD44 | P16070 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24628702 | 0.71 | GRM5 (0.39) | DRD2DRD1GRM5DRD4DRD5 | |
| SCHEMBL20522616 | 0.70 | PNMT (0.52) | DRD2DRD1PNMTCD44MAOB | |
| SCHEMBL17462463 | 0.69 | PNMT (0.50) | DRD2DRD1PNMTCD44MAOB | |
| Bromide SCHEMBL30254921 | 0.69 | PNMT (0.50) | DRD2DRD1PNMTCD44MAOB | |
| SCHEMBL15503204 | 0.67 | PNMT (0.49) | DRD2DRD1PNMT | |
| SCHEMBL15503053 | 0.67 | PNMT (0.49) | DRD2DRD1PNMT | |
| SCHEMBL31013896 | 0.67 | PNMT (0.49) | DRD2DRD1PNMT | |
| SCHEMBL24629247 | 0.66 | KDM4E (0.38) | GRM5 | |
| Bromide SCHEMBL15515105 | 0.66 | PNMT (0.47) | DRD2DRD1PNMT | |
| SCHEMBL20211704 | 0.63 | APP (0.60) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022149617-A1 | COMPOUND LIBRARY | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |