Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 13/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24629246 | 0.81 | MAOB (0.43) | GRM5 | |
| SCHEMBL24629247 | 0.77 | KDM4E (0.38) | GRM5 | |
| SCHEMBL24628992 | 0.76 | PDE4B (0.41) | PDE4D | |
| SCHEMBL26895796 | 0.75 | ESR2 (0.56) | GRM5ESR2 | |
| SCHEMBL26854537 | 0.73 | GRM5 (0.46) | GRM5 | |
| SCHEMBL24628686 | 0.71 | DRD2 (0.39) | GRM5DRD2DRD1DRD4DRD5 | |
| SCHEMBL26895925 | 0.71 | ALDH1A1 (0.46) | PDE4D | |
| SCHEMBL24628556 | 0.71 | MEN1 (0.41) | GRM5ESR2 | |
| SCHEMBL26896015 | 0.70 | PRMT5 (0.37) | ESR2DRD3 | |
| SCHEMBL11744257 | 0.68 | ESR2 (0.54) | PDE4DESR2DRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149617-A1 | COMPOUND LIBRARY | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |