Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24628556 | 0.86 | MEN1 (0.41) | KDM4EGRM5USP2NPC1ALDH1A1 | |
| SCHEMBL24629246 | 0.86 | MAOB (0.43) | KDM4EGRM5ALDH1A1SMN1; SMN2 | |
| SCHEMBL26896015 | 0.80 | PRMT5 (0.37) | — | |
| SCHEMBL24628702 | 0.77 | GRM5 (0.39) | GRM5 | |
| SCHEMBL26854537 | 0.74 | GRM5 (0.46) | GRM5LMNAHPGD | |
| SCHEMBL26895796 | 0.72 | ESR2 (0.56) | GRM5MAPT | |
| SCHEMBL16061897 | 0.71 | MEN1 (0.57) | KDM4EAKR1C3USP2NPC1ALDH1A1 | |
| SCHEMBL30109424 | 0.71 | MEN1 (0.57) | KDM4EAKR1C3USP2NPC1ALDH1A1 | |
| SCHEMBL24628992 | 0.69 | PDE4B (0.41) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL6380662 | 0.68 | MEN1 (0.54) | KDM4EAKR1C3USP2CHEK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022149617-A1 | COMPOUND LIBRARY | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |