Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.44 |
| ▸ | PLG | P00747 | 4/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26657492 | 0.93 | F10 (0.45) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL24628709 | 0.82 | F10 (0.43) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL24628769 | 0.81 | ESR2 (0.44) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL26657561 | 0.80 | F10 (0.50) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL30670212 | 0.79 | F10 (0.41) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL26657625 | 0.79 | F10 (0.41) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL24628746 | 0.72 | ESR2 (0.56) | GPR119HPGDNR1H2ADORA1KDM4E | |
| SCHEMBL6671296 | 0.72 | HRH3 (0.57) | F10PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL20558294 | 0.69 | ADORA1 (0.51) | NR1H2ADORA1ALDH1A1ESR2 | |
| SCHEMBL30670170 | 0.69 | ADORA1 (0.51) | NR1H2ADORA1ALDH1A1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149617-A1 | COMPOUND LIBRARY | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |