Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.41 |
| ▸ | YAP1 | P46937 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24628709 | 0.93 | F10 (0.43) | ESR2F10PLGPRSS1PRSS2 | |
| SCHEMBL30670212 | 0.92 | F10 (0.41) | ESR2F10PLGPRSS1PRSS2 | |
| SCHEMBL26657625 | 0.92 | F10 (0.41) | ESR2F10PLGPRSS1PRSS2 | |
| SCHEMBL26657492 | 0.88 | F10 (0.45) | ESR2F10PLGPRSS1PRSS2 | |
| SCHEMBL21687178 | 0.83 | ESR2 (0.53) | ESR2NR1H2GPR119YAP1MAPK1 | |
| SCHEMBL24628707 | 0.81 | F10 (0.44) | ESR2F10PLGPRSS1PRSS2 | |
| SCHEMBL6671296 | 0.78 | HRH3 (0.57) | ESR2F10PLGPRSS1PRSS2 | |
| SCHEMBL24628711 | 0.77 | F10 (0.47) | ESR2F10PLGPRSS1PRSS2 | |
| SCHEMBL24628738 | 0.77 | GPR119 (0.41) | GPR119YAP1PRMT5HRH3CA12 | |
| SCHEMBL30670191 | 0.77 | GPR119 (0.41) | GPR119YAP1PRMT5HRH3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149617-A1 | COMPOUND LIBRARY | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |