Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.50 |
| ▸ | PLG | P00747 | 6/20 | 0.50 |
| ▸ | F2 | P00734 | 4/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | YAP1 | P46937 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24628711 | 0.88 | F10 (0.47) | F10PLGF2PRSS1PRSS2 | |
| SCHEMBL24629039 | 0.87 | F10 (0.48) | F10PLGF2PRSS1PRSS2 | |
| SCHEMBL26657492 | 0.87 | F10 (0.45) | F10PLGF2PRSS1PRSS2 | |
| SCHEMBL24628707 | 0.80 | F10 (0.44) | F10PLGF2PRSS1PRSS2 | |
| SCHEMBL6672245 | 0.78 | F10 (0.57) | F10PLGF2PRSS1PRSS2 | |
| SCHEMBL24628709 | 0.77 | F10 (0.43) | F10PLGF2PRSS1PRSS2 | |
| SCHEMBL30670191 | 0.77 | GPR119 (0.41) | GPR119YAP1HRH3 | |
| SCHEMBL24628738 | 0.77 | GPR119 (0.41) | GPR119YAP1HRH3 | |
| SCHEMBL24628769 | 0.75 | ESR2 (0.44) | F10PLGF2PRSS1PRSS2 | |
| SCHEMBL30670212 | 0.74 | F10 (0.41) | F10PLGF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |