Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | YAP1 | P46937 | 3/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30670191 | 1.00 | GPR119 (0.41) | GPR119HRH3YAP1PRMT5WDR77 | |
| SCHEMBL30670212 | 0.85 | F10 (0.41) | GPR119HRH3YAP1PRMT5CA12 | |
| SCHEMBL26657625 | 0.85 | F10 (0.41) | GPR119HRH3YAP1PRMT5CA12 | |
| SCHEMBL21687177 | 0.78 | ESR2 (0.48) | GPR119HRH3YAP1 | |
| SCHEMBL24628711 | 0.78 | F10 (0.47) | GPR119HRH3YAP1PRMT5WDR77 | |
| SCHEMBL24628769 | 0.77 | ESR2 (0.44) | GPR119HRH3YAP1PRMT5CA12 | |
| SCHEMBL24628709 | 0.77 | F10 (0.43) | GPR119HRH3YAP1PRMT5 | |
| SCHEMBL26657561 | 0.77 | F10 (0.50) | GPR119HRH3YAP1 | |
| SCHEMBL30156685 | 0.77 | NR1H2 (0.47) | GPR119HRH3PRMT5WDR77 | |
| SCHEMBL24914051 | 0.77 | NR1H2 (0.47) | GPR119HRH3PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |
| CN-116783160-A | Libraries of compounds | 中外制药株式会社 | 2023-09-19 | — | — | CN | disclosed |
| WO-2022149617-A1 | COMPOUND LIBRARY | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |