Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.54 |
| ▸ | SNCA | P37840 | 2/20 | 0.54 |
| ▸ | NQO2 | P16083 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149098 | 0.85 | MEN1 (0.63) | PTPN1SNCANPC1RAB9AMAPT | |
| SCHEMBL26815735 | 0.83 | NPC1 (0.59) | DEGS1PTPN1SNCANQO2NPC1 | |
| SCHEMBL24628629 | 0.82 | SNCA (0.60) | DEGS1PTPN1SNCANQO2NPC1 | |
| SCHEMBL20284045 | 0.79 | DEGS1 (0.86) | DEGS1PTPN1SNCANQO2NPC1 | |
| SCHEMBL15847328 | 0.79 | NPC1 (0.64) | NPC1RAB9AMAPTMAOB | |
| SCHEMBL20284430 | 0.79 | PTPN1 (0.86) | DEGS1PTPN1SNCANPC1RAB9A | |
| SCHEMBL12644762 | 0.77 | NQO2 (0.68) | DEGS1SNCANQO2NPC1RAB9A | |
| SCHEMBL26815658 | 0.77 | RAB9A (0.66) | DEGS1PTPN1NQO2NPC1RAB9A | |
| SCHEMBL123046 | 0.76 | MEN1 (0.63) | PTPN1SNCANPC1RAB9AMAPT | |
| SCHEMBL23326911 | 0.75 | KCNQ3 (0.63) | DEGS1SNCANQO2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022149617-A1 | COMPOUND LIBRARY | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |