Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.57 |
| ▸ | NQO2 | P16083 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26815558 | 0.88 | MEN1 (0.65) | NPC1RAB9ASMN1; SMN2DEGS1KMT2A | |
| SCHEMBL31709720 | 0.85 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL24628764 | 0.83 | DEGS1 (0.57) | NPC1RAB9ADEGS1NQO2KMT2A | |
| SCHEMBL24628415 | 0.82 | DEGS1 (0.60) | NPC1RAB9ADEGS1NQO2KMT2A | |
| SCHEMBL6781288 | 0.80 | DEGS1 (0.69) | NPC1RAB9ADEGS1KMT2AMAPT | |
| SCHEMBL20284045 | 0.79 | DEGS1 (0.86) | NPC1RAB9ASMN1; SMN2DEGS1NQO2 | |
| SCHEMBL4751142 | 0.79 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL20284419 | 0.79 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2DEGS1NQO2 | |
| SCHEMBL24629178 | 0.78 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL12644762 | 0.77 | NQO2 (0.68) | NPC1RAB9ASMN1; SMN2DEGS1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |