Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 3/20 | 0.60 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.57 |
| ▸ | NQO2 | P16083 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TOP1 | P11387 | 2/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.49 |
| ▸ | KDM6B | O15054 | 1/20 | 0.48 |
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.48 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.48 |
| ▸ | ESRRG | P62508 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24628764 | 0.82 | DEGS1 (0.57) | SNCADEGS1PTPN1NQO2NPC1 | |
| SCHEMBL24628415 | 0.82 | DEGS1 (0.60) | SNCADEGS1PTPN1NQO2NPC1 | |
| SCHEMBL20284045 | 0.82 | DEGS1 (0.86) | SNCADEGS1PTPN1NQO2NPC1 | |
| SCHEMBL20284430 | 0.81 | PTPN1 (0.86) | SNCADEGS1PTPN1NPC1RAB9A | |
| SCHEMBL8769844 | 0.77 | DEGS1 (0.77) | SNCADEGS1PTPN1NQO2NPC1 | |
| SCHEMBL24628731 | 0.76 | NPC1 (0.71) | DEGS1PTPN1NQO2NPC1RAB9A | |
| SCHEMBL8420639 | 0.76 | DEGS1 (0.75) | SNCADEGS1PTPN1NQO2NPC1 | |
| SCHEMBL900928 | 0.76 | DEGS1 (0.75) | SNCADEGS1PTPN1NQO2NPC1 | |
| SCHEMBL899585 | 0.76 | DEGS1 (0.75) | SNCADEGS1PTPN1NQO2NPC1 | |
| SCHEMBL9342931 | 0.76 | DEGS1 (0.81) | SNCADEGS1PTPN1NQO2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022149617-A1 | COMPOUND LIBRARY | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |