Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP4 | P49662 | 1/20 | 0.42 |
| ▸ | CASP5 | P51878 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10666648 | 0.83 | MEN1 (0.70) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL26054244 | 0.76 | ALDH1A1 (0.63) | KMT2AALDH1A1KDM4EGAALMNA | |
| SCHEMBL12511057 | 0.72 | ACHE (0.74) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL7426743 | 0.71 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL1589671 | 0.70 | BACE1 (0.50) | ALDH1A1 | |
| SCHEMBL29901077 | 0.70 | BACE1 (0.50) | ALDH1A1 | |
| SCHEMBL4953327 | 0.70 | BACE1 (0.50) | ALDH1A1POLBHTT | |
| SCHEMBL13479650 | 0.69 | MEN1 (0.73) | MEN1KMT2AALDH1A1POLBACHE | |
| SCHEMBL7374846 | 0.69 | KDM4E (0.63) | ALDH1A1KDM4EPOLBLMNASMN1; SMN2 | |
| SCHEMBL16803417 | 0.69 | BACE1 (0.49) | ALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149617-A1 | COMPOUND LIBRARY | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |