Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.46 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.46 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.46 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24628828 | 0.83 | MEN1 (0.50) | MEN1KMT2AKDM4EHTTTDP1 | |
| SCHEMBL315973 | 0.81 | MEN1 (0.97) | MEN1KMT2ATDP1L3MBTL1POLB | |
| SCHEMBL14351628 | 0.78 | ACHE (0.68) | MEN1KMT2AKDM4EHTTTDP1 | |
| SCHEMBL2372693 | 0.76 | ACHE (0.70) | MEN1KMT2AKDM4EHTTTDP1 | |
| SCHEMBL26054244 | 0.75 | ALDH1A1 (0.63) | KMT2AKDM4EMAPTHTTTDP1 | |
| SCHEMBL6891634 | 0.75 | MEN1 (0.59) | MEN1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL29901077 | 0.74 | BACE1 (0.50) | ALDH1A1 | |
| SCHEMBL4953327 | 0.74 | BACE1 (0.50) | HTTPOLBALDH1A1 | |
| SCHEMBL1589671 | 0.74 | BACE1 (0.50) | ALDH1A1 | |
| SCHEMBL16054847 | 0.74 | L3MBTL1 (0.61) | MEN1KMT2AKDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4767769-A | HISTAMINE-H2 ANTAGONISTS | THE BOOTS COMPANY PLC (GB) | 1988-08-30 | — | — | US | disclosed |
| EP-0172631-A1 | Therapeutic agents | The Boots Company PLC (GB) | 1986-02-26 | — | — | EP | disclosed |