Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 4/20 | 0.38 |
| ▸ | DPYD | Q12882 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722932 | 0.79 | XDH (0.36) | TYMSPNPCYP3A4BLM | |
| SCHEMBL28919394 | 0.79 | FGFR1 (0.36) | TYMSPNPCYP3A4BLMDYRK1A | |
| SCHEMBL20206646 | 0.76 | PNP (0.36) | PNP | |
| SCHEMBL25899172 | 0.75 | L3MBTL1 (0.32) | PNPCYP3A4BLM | |
| SCHEMBL25899106 | 0.75 | CHEK1 (0.35) | TYMSPNPCYP3A4BLMCHEK1 | |
| SCHEMBL20202010 | 0.72 | PNP (0.36) | PNP | |
| SCHEMBL20206756 | 0.72 | PNP (0.39) | TYMSPNP | |
| SCHEMBL15061831 | 0.71 | TYMS (0.48) | TYMSCHEK1DYRK1A | |
| SCHEMBL20202013 | 0.70 | PNP (0.39) | PNP | |
| SCHEMBL20202014 | 0.67 | PNP (0.37) | PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272307-A1 | BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS | LYCIA THERAPEUTICS, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022150721-A1 | BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS | LYCIA THERAPEUTICS, INC. (US) | 2022-07-14 | — | — | WO | disclosed |