Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | QDPR | P09417 | 1/20 | 0.33 |
| ▸ | ESRRB | O95718 | 2/20 | 0.32 |
| ▸ | ESRRG | P62508 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24629247 | 0.80 | KDM4E (0.38) | — | |
| SCHEMBL24629246 | 0.79 | MAOB (0.43) | — | |
| SCHEMBL24628556 | 0.74 | MEN1 (0.41) | ESR1ESR2 | |
| SCHEMBL24628702 | 0.70 | GRM5 (0.39) | DRD3ESR2 | |
| SCHEMBL12273056 | 0.69 | SLC18A3 (0.68) | SLC18A3SIGMAR1ESR1NAMPTP2RY14 | |
| SCHEMBL24628686 | 0.69 | DRD2 (0.39) | DRD3 | |
| SCHEMBL24628690 | 0.67 | SLC18A3 (0.33) | PRMT5WDR77SLC18A3SIGMAR1NAMPT | |
| SCHEMBL26895796 | 0.64 | ESR2 (0.56) | PRMT5WDR77SIGMAR1ESR2NAMPT | |
| SCHEMBL26854537 | 0.62 | GRM5 (0.46) | NAMPT | |
| SCHEMBL12279471 | 0.62 | HTR3A (0.56) | DRD3SLC18A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |