Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24629610 | 0.89 | POLB (0.41) | KDM4ELMNATSHRL3MBTL1ALDH1A1 | |
| SCHEMBL29769136 | 0.89 | POLB (0.41) | KDM4ELMNATSHRL3MBTL1ALDH1A1 | |
| SCHEMBL24629459 | 0.86 | LMNA (0.43) | KDM4ELMNATSHRL3MBTL1NOD2 | |
| SCHEMBL24629460 | 0.84 | TSHR (0.41) | KDM4ELMNATSHRL3MBTL1NOD2 | |
| SCHEMBL24630033 | 0.82 | LMNA (0.39) | KDM4ELMNATSHRL3MBTL1NOD2 | |
| SCHEMBL29769155 | 0.79 | MAPK1 (0.45) | KDM4ELMNAL3MBTL1ALDH1A1HTT | |
| SCHEMBL24629971 | 0.79 | MAPK1 (0.45) | KDM4ELMNAL3MBTL1ALDH1A1HTT | |
| SCHEMBL24629923 | 0.78 | LMNA (0.40) | KDM4ELMNAALDH1A1HTTGAA | |
| SCHEMBL24629608 | 0.78 | KMT2A (0.46) | KDM4ELMNAALDH1A1HTTGAA | |
| SCHEMBL29769220 | 0.78 | KMT2A (0.46) | KDM4ELMNAALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150574-A1 | INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE | CORNELL UNIVERSITY (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2022150574-A1 | INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE | CORNELL UNIVERSITY (US) | 2022-07-14 | — | — | WO | disclosed |