Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.38 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29769136 | 1.00 | POLB (0.41) | POLBHPGDALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL24629474 | 0.89 | KDM4E (0.41) | POLBHPGDALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL24629923 | 0.81 | LMNA (0.40) | POLBALDH1A1KDM4ERAB9ALMNA | |
| SCHEMBL29769063 | 0.80 | POLB (0.39) | POLBHPGDALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL29769155 | 0.80 | MAPK1 (0.45) | ALDH1A1KDM4EL3MBTL1RAB9ALMNA | |
| SCHEMBL24629971 | 0.80 | MAPK1 (0.45) | ALDH1A1KDM4EL3MBTL1RAB9ALMNA | |
| SCHEMBL29769220 | 0.80 | KMT2A (0.46) | ALDH1A1KDM4ERAB9ALMNAMAPK1 | |
| SCHEMBL24629608 | 0.80 | KMT2A (0.46) | ALDH1A1KDM4ERAB9ALMNAMAPK1 | |
| SCHEMBL27041691 | 0.79 | RXFP1 (0.35) | POLBALDH1A1KDM4ELMNA | |
| SCHEMBL24629466 | 0.78 | ALDH1A1 (0.36) | POLBHPGDALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150574-A1 | INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE | CORNELL UNIVERSITY (US) | 2022-07-14 | — | — | WO | disclosed |