SCHEMBL246295

SCHEMBL246295

O=C(Oc1ccccc1)Oc1ccccc1C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.40
HPGD P15428 4/20 0.40
KDM4E B2RXH2 3/20 0.40
TDP1 Q9NUW8 4/20 0.39
ATM Q13315 3/20 0.39
MAOB P27338 1/20 0.38
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
ALDH1A1 P00352 6/20 0.36
MAPT P10636 5/20 0.35
KMT2A Q03164 2/20 0.35
PPARG P37231 1/20 0.35
NCOA2 Q15596 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
TSHR P16473 2/20 0.35
ALOX15 P16050 1/20 0.35
ESR1 P03372 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19181694 0.93 KDM4E (0.44) HSD17B10HPGDKDM4ETDP1ATM
SCHEMBL247688 0.84 ATM (0.43) HSD17B10HPGDKDM4ETDP1ATM
SCHEMBL11137016 0.83 MAOB (0.54) HSD17B10HPGDKDM4ETDP1ATM
SCHEMBL27516773 0.82 TDP1 (0.42) HSD17B10HPGDKDM4ETDP1ATM
SCHEMBL247585 0.81 TDP1 (0.58) HSD17B10HPGDKDM4ETDP1ATM
SCHEMBL246296 0.80 MAPT (0.51) HSD17B10HPGDKDM4ETDP1ATM
SCHEMBL1157159 0.80 HPGD (0.40) HSD17B10HPGDKDM4ETDP1ATM
SCHEMBL246240 0.80 KDM4E (0.40) HSD17B10HPGDKDM4ETDP1ATM
SCHEMBL236826 0.78 MAPT (0.53) TDP1ATML3MBTL1ALDH1A1MAPT
SCHEMBL245087 0.76 ATM (0.37) HSD17B10HPGDKDM4ETDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3174935-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED OPTICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-21 EP disclosed
EP-3174934-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED RHEOLOGICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-14 EP disclosed
EP-3227374-B1 COPOLYCARBONATE COMPOUNDS WITH IMPROVED RHEOLOGICAL AND OPTICAL PROPERTIES CONTAINING DIGLYCEROLESTER COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-06-01 EP disclosed
US-10323145-B2 Copolycarbonate compositions with cyclic and linear oligomers and improved optical properties COVESTRO DEUTSCHLAND AG (DE) 2019-06-18 US disclosed
US-20190143582-A1 COPOLYCARBONATE AS A SUPPORTING MATERIAL IN 3-D PRINTING COVESTRO DEUTSCHLAND AG (DE) 2019-05-16 US disclosed
EP-2496636-B1 MORE FLAME-RETARDANT POLYCARBONATE COMPOSITION FOR USE IN EXTRUDED PRODUCTS COVESTRO DEUTSCHLAND AG (DE) 2019-05-15 EP disclosed
US-10272654-B2 Polycarbonate composition having improved flame resistance for extrusion applications COVESTRO DEUTSCHLAND AG (DE) 2019-04-30 US disclosed
US-20180179378-A1 Copolycarbonate Compositions with Cyclic and Linear Oligomers and Improved Optical Properties COVESTRO DEUTSCHLAND AG (DE) 2018-06-28 US disclosed
US-9969879-B2 Copolycarbonate compositions with branch structures and linear oligomers and improved rheological properties COVESTRO DEUTSCHLAND AG (DE) 2018-05-15 US disclosed
US-20170362431-A1 COPOLYCARBONATE COMPOSITIONS WITH IMPROVED RHEOLOGICAL AND OPTICAL PROPERTIES CONTAINING DIGLYCEROLESTERS COVESTRO DEUTSCHLAND AG (DE) 2017-12-21 US disclosed
US-20030027971-A1 Preparation of copolycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-02-06 US disclosed
EP-1277781-A2 Process for preparing copolycarbonates Bayer Aktiengesellschaft (DE) 2003-01-22 EP disclosed
EP-1270638-A2 Process and use of polyestercarbonates Bayer Aktiengesellschaft (DE) 2003-01-02 EP disclosed
EP-1266924-A2 Polycarbonates, polyestercarbonates and polyesters having branched endgroups BAYER AG (DE) 2002-12-18 EP disclosed
US-20020188091-A1 Process for continuous production of polycarbonates and a reactor therefor COVESTRO DEUTSCHLAND AG (DE) 2002-12-12 US disclosed
WO-2002085967-A1 METHOD FOR CONTINUOUSLY PRODUCING POLYCARBONATES ACCORDING TO THE MELT TRANSESTERIFICATION METHOD BAYER AKTIENGESELLSCHAFT (DE) 2002-10-31 WO disclosed
EP-1253163-A1 Process for continuously preparing polycarbonates by transesterification BAYER AG (DE) 2002-10-30 EP disclosed
WO-2002077067-A2 METHOD FOR PRODUCING POLYCARBONATES BAYER AKTIENGESELLSCHAFT (DE) 2002-10-03 WO disclosed
WO-2002077066-A1 METHOD FOR PRODUCING OLIGOCARBONATES BAYER AKTIENGESELLSCHAFT (DE) 2002-10-03 WO disclosed
US-20020137874-A1 Process for producing oligocarbonates COVESTRO DEUTSCHLAND AG (DE) 2002-09-26 US disclosed