SCHEMBL245087

SCHEMBL245087

CC(C)(c1ccccc1)c1cccc(OC(=O)Oc2ccccc2)c1C(C)(C)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
MAPT P10636 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
NPSR1 Q6W5P4 2/20 0.35
KDM4E B2RXH2 5/20 0.35
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
POLB P06746 1/20 0.34
ALDH1A1 P00352 5/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
RAB9A P51151 1/20 0.33
HTT P42858 1/20 0.33
MAOB P27338 1/20 0.33
ESR1 P03372 1/20 0.33
CYP3A4 P08684 1/20 0.33
ESR2 Q92731 1/20 0.33
ELANE P08246 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL247099 0.94 TDP1 (0.40) ATMTDP1MAPTL3MBTL1KDM4E
SCHEMBL247688 0.88 ATM (0.43) ATMTDP1MAPTL3MBTL1NPSR1
SCHEMBL1870707 0.86 ATM (0.37) ATMTDP1MAPTKDM4EHPGD
SCHEMBL29601094 0.85 TDP1 (0.40) ATMTDP1MAPTL3MBTL1KDM4E
SCHEMBL247100 0.85 TDP1 (0.40) ATMTDP1MAPTL3MBTL1KDM4E
SCHEMBL1157233 0.83 ATM (0.37) ATMTDP1MAPTNPSR1KDM4E
SCHEMBL1673995 0.82 TDP1 (0.47) ATMTDP1MAPTL3MBTL1KDM4E
SCHEMBL247541 0.81 ATM (0.46) ATMTDP1MAPTL3MBTL1NPSR1
SCHEMBL27488778 0.81 TDP1 (0.37) ATMTDP1KDM4EPOLBALDH1A1
SCHEMBL27819527 0.81 ATM (0.37) ATMTDP1MAPTKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3174935-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED OPTICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-21 EP disclosed
EP-3174934-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED RHEOLOGICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-14 EP disclosed
EP-3227374-B1 COPOLYCARBONATE COMPOUNDS WITH IMPROVED RHEOLOGICAL AND OPTICAL PROPERTIES CONTAINING DIGLYCEROLESTER COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-06-01 EP disclosed
EP-3452530-B1 COPOLYCARBONATE AS SUPPORT MATERIAL FOR 3D PRINTING COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2020-09-30 EP disclosed
EP-3227387-B1 COPOLYCARBONATE COMPOUNDS WITH IMPROVED PROCESSABILITY CONTAINING PE WAXES COVESTRO DEUTSCHLAND AG (DE) 2020-03-11 EP disclosed
US-10323145-B2 Copolycarbonate compositions with cyclic and linear oligomers and improved optical properties COVESTRO DEUTSCHLAND AG (DE) 2019-06-18 US disclosed
US-20190143582-A1 COPOLYCARBONATE AS A SUPPORTING MATERIAL IN 3-D PRINTING COVESTRO DEUTSCHLAND AG (DE) 2019-05-16 US disclosed
EP-2496636-B1 MORE FLAME-RETARDANT POLYCARBONATE COMPOSITION FOR USE IN EXTRUDED PRODUCTS COVESTRO DEUTSCHLAND AG (DE) 2019-05-15 EP disclosed
US-10272654-B2 Polycarbonate composition having improved flame resistance for extrusion applications COVESTRO DEUTSCHLAND AG (DE) 2019-04-30 US disclosed
EP-3452530-A1 COPOLYCARBONATE AS A SUPPORTING MATERIAL IN 3-D PRINTING Covestro Deutschland AG (DE) 2019-03-13 EP disclosed
WO-2003014187-A1 METHOD FOR OPTIMISING THE PRODUCTION OF POLYCARBONATE BY MEANS OF MELT TRANSESTERIFICATION BAYER AKTIENGESELLSCHAFT (DE) 2003-02-20 WO disclosed
US-20030027971-A1 Preparation of copolycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-02-06 US disclosed
EP-1277781-A2 Process for preparing copolycarbonates Bayer Aktiengesellschaft (DE) 2003-01-22 EP disclosed
EP-1270638-A2 Process and use of polyestercarbonates Bayer Aktiengesellschaft (DE) 2003-01-02 EP disclosed
US-20020188091-A1 Process for continuous production of polycarbonates and a reactor therefor COVESTRO DEUTSCHLAND AG (DE) 2002-12-12 US disclosed
WO-2002085967-A1 METHOD FOR CONTINUOUSLY PRODUCING POLYCARBONATES ACCORDING TO THE MELT TRANSESTERIFICATION METHOD BAYER AKTIENGESELLSCHAFT (DE) 2002-10-31 WO disclosed
EP-1253163-A1 Process for continuously preparing polycarbonates by transesterification BAYER AG (DE) 2002-10-30 EP disclosed
WO-2002077067-A2 METHOD FOR PRODUCING POLYCARBONATES BAYER AKTIENGESELLSCHAFT (DE) 2002-10-03 WO disclosed
WO-2002077066-A1 METHOD FOR PRODUCING OLIGOCARBONATES BAYER AKTIENGESELLSCHAFT (DE) 2002-10-03 WO disclosed
US-20020137874-A1 Process for producing oligocarbonates COVESTRO DEUTSCHLAND AG (DE) 2002-09-26 US disclosed