Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24629466 | 0.77 | ALDH1A1 (0.36) | MEN1PKMKMT2A | |
| SCHEMBL24629878 | 0.74 | AR (0.41) | MEN1PKMKMT2AAR | |
| SCHEMBL24630010 | 0.69 | PPARG (0.37) | MEN1KMT2A | |
| SCHEMBL24629880 | 0.67 | TRPV4 (0.32) | TRPV4 | |
| SCHEMBL12320911 | 0.65 | AR (0.36) | MEN1PKMKMT2AAR | |
| SCHEMBL22579369 | 0.64 | MEN1 (0.43) | MEN1PKMKMT2AAR | |
| SCHEMBL7129180 | 0.64 | KDM4E (0.44) | MEN1KMT2ATRPV4 | |
| SCHEMBL744084 | 0.64 | TRPV4 (0.40) | ARTRPV4 | |
| SCHEMBL806475 | 0.64 | RXFP1 (0.49) | MEN1KMT2AAR | |
| SCHEMBL806481 | 0.62 | AR (0.32) | MEN1KMT2AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150574-A1 | INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE | CORNELL UNIVERSITY (US) | 2022-07-14 | — | — | WO | disclosed |