SCHEMBL246300

SCHEMBL246300

CCCCCC(=C(C#N)C(=O)O)c1ccc(OC)cc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.46
NR1I2 O75469 1/20 0.44
PDE4B Q07343 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC2 Q92769 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
CNR1 P21554 3/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
KDM4E B2RXH2 1/20 0.41
CRHBP P24387 1/20 0.41
HTT P42858 1/20 0.41
CRHR2 Q13324 1/20 0.41
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9214719 0.99 PTGS2 (0.46) PTGS2NR1I2PDE4BHDAC3HDAC1
SCHEMBL10591928 0.91 NR1I2 (0.47) PTGS2NR1I2PDE4BHDAC3HDAC1
SCHEMBL9218096 0.85 MMP2 (0.42) NR1I2PDE4BHDAC1NPC1RAB9A
SCHEMBL3824921 0.85 EPHX2 (0.51) NPC1RAB9AALDH1A1
SCHEMBL27352443 0.85 NR1I2 (0.59) PTGS2NR1I2HDAC3HDAC1HDAC2
SCHEMBL226431 0.85 NR1I2 (0.59) PTGS2NR1I2HDAC3HDAC1HDAC2
SCHEMBL27509228 0.83 PTGS2 (0.47) PTGS2HDAC3HDAC1HDAC2NPC1
SCHEMBL8359733 0.83 EPHX2 (0.49) HDAC3HDAC2ALDH1A1CA1CA2
SCHEMBL27832896 0.80 PTGS2 (0.56) PTGS2RAB9AALDH1A1LMNATSHR
SCHEMBL4964670 0.78 CA1 (0.44) NR1I2PDE4BHDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3604454-B1 COATED PIGMENT, AQUEOUS PIGMENT DISPERSION, USE THEREOF, AND PRODUCTION METHOD THEREFOR ARTIENCE CO LTD (JP) 2024-08-07 EP disclosed
US-11168228-B2 Ink, image forming method, image forming device, and recorded matter RICOH COMPANY, LTD. (JP) 2021-11-09 US disclosed
US-10851253-B2 Image forming method and image forming apparatus RICOH COMPANY, LTD. (JP) 2020-12-01 US disclosed
US-10717297-B2 Inkjet recording method and inkjet recording apparatus RICOH COMPANY, LTD. (JP) 2020-07-21 US disclosed
EP-3604454-A1 COATED PIGMENT, AQUEOUS PIGMENT DISPERSION, USE THEREOF, AND PRODUCTION METHOD THEREFOR Toyo Ink SC Holdings Co., Ltd. (JP) 2020-02-05 EP disclosed
US-20190300731-A1 INK, IMAGE FORMING METHOD, IMAGE FORMING DEVICE, AND RECORDED MATTER RICOH COMPANY, LTD. (JP) 2019-10-03 US disclosed
US-20190284412-A1 IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2019-09-19 US disclosed
US-10283711-B2 Method of producing organic EL ink and method of manufacturing organic EL device JOLED INC. (JP) 2019-05-07 US disclosed
US-20190048216-A1 INKJET RECORDING METHOD AND INKJET RECORDING APPARATUS RICOH COMPANY, LTD. (JP) 2019-02-14 US disclosed
US-9982151-B2 Aqueous ink for inkjet, inkjet recording method, inkjet recorded matter, and inkjet recording device RICOH COMPANY, LTD. (JP) 2018-05-29 US disclosed
WO-2006030930-A1 RECORDING INK, INK CARTRIDGE, INK RECORD, INKJET RECORDING APPARATUS, AND INKJET RECORDING METHOD RICOH COMPANY, LTD. (JP) 2006-03-23 WO disclosed
US-20060057363-A1 Method for forming a glittering coating film and glittering coated object NIPPON PAINT AUTOMOTIVE COATINGS CO., LTD. (JP) 2006-03-16 US disclosed
US-20050117008-A1 Recording ink and manufacturing method thereof, ink cartridge, ink recorded matter, inkjet recording apparatus, and inkjet recording method RICOH COMPANY, LTD. (JP) 2005-06-02 US disclosed
EP-1095956-A2 Thermoset Polyurethane resin and method for the production thereof Mitsui Chemicals, Inc. (JP) 2001-05-02 EP disclosed
US-5798407-A KNEADING WATER ABSORPTIVE RESIN, ADDING THERMOPLASTIC MODIFIED ETHYLENE POLYMER, OPTIONAL THERMOPLASTIC POLYMER, ADDITIVE, MELT KNEADING MIXTURE TO PRODUCE HYDROPHILIC RESIN COMPOSITION MITSUBISHI CHEMICAL CORPORATION (JP) 1998-08-25 US disclosed
US-5319016-A Blend of vinyl polymer, modified polyolefin and hydrogenated vinyl-aliphatic diene block polymer in solvent CHISSO CORPORATION (JP) 1994-06-07 US disclosed
EP-0406828-B1 Emulsion adhesive composition and process for production thereof CHISSO CORP (JP) 1994-05-11 EP disclosed
EP-0406828-A1 Emulsion adhesive composition and process for production thereof Chisso Corporation (JP) 1991-01-09 EP disclosed
US-4525504-A 1,4-CYCLOHEXANDEICARBOXYLIC ACID AND 2,2,4,4-TETRAMETHYL-1,3-CYCLOBUTANEDIOL, UV AND HINDERED AMINE STABILIZERS EASTMAN KODAK COMPANY (US) 1985-06-25 US disclosed
US-4524165-A 1,4-CYCLOHEXANEDICARBOXYLIC ACID AND 1,4-CYCLOHEXANE DIOL MONOMERS; POLYALKYLENE GLCOLS; STABILIZER MIXTURE EASTMAN KODAK COMPANY (US) 1985-06-18 US disclosed