Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | LGMN | Q99538 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29769079 | 1.00 | MAPT (0.61) | MAPTGAASMN1; SMN2LGMNALDH1A1 | |
| SCHEMBL21590200 | 0.81 | MAPT (0.59) | MAPTGAAALDH1A1KDM4ELMNA | |
| SCHEMBL3676602 | 0.80 | MAPT (0.42) | MAPTGAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4377045 | 0.78 | MAPT (0.71) | MAPTGAASMN1; SMN2LGMNALDH1A1 | |
| SCHEMBL31491393 | 0.78 | MAPT (0.71) | MAPTGAASMN1; SMN2LGMNALDH1A1 | |
| SCHEMBL29715972 | 0.76 | MAPT (1.00) | MAPTGAASMN1; SMN2LGMNALDH1A1 | |
| SCHEMBL78364 | 0.76 | MAPT (1.00) | MAPTGAASMN1; SMN2LGMNALDH1A1 | |
| SCHEMBL23064481 | 0.76 | ACHE (0.47) | MAPTGAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL24630259 | 0.75 | ALDH1A1 (0.65) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL2744374 | 0.75 | MAPT (0.67) | MAPTGAASMN1; SMN2LGMNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011610-A1 | BENZODIOXANE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京红云生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |
| WO-2022150574-A1 | INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE | CORNELL UNIVERSITY (US) | 2022-07-14 | — | — | WO | disclosed |