Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | GAA | P10253 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | LGMN | Q99538 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | S100B | P04271 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31491393 | 1.00 | MAPT (0.71) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| Sulfuric Acid SCHEMBL7805727 | 0.90 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL7514624 | 0.86 | ALDH1A1 (0.53) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL14280213 | 0.85 | LGMN (0.71) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL78364 | 0.83 | MAPT (1.00) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL29715972 | 0.83 | MAPT (1.00) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL2711166 | 0.83 | LGMN (0.74) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL3723011 | 0.81 | ALDH1A1 (0.59) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL3724717 | 0.81 | KDM4E (0.67) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL1136197 | 0.81 | ALDH1A1 (0.67) | MAPTSMN1; SMN2GAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025047698-A1 | PHOTOSENSITIVE COMPOSITION, CURED PRODUCT, METHOD FOR PRODUCING SAME, LIQUID CRYSTAL DEVICE, SEMICONDUCTOR DEVICE, POLYMER, AND COMPOUND | JSR株式会社 | 2025-03-06 | — | — | WO | disclosed |
| US-11787905-B2 | Polyamide compound | TOYOTA BOSHOKU KABUSHIKI KAISHA (JP) | 2023-10-17 | — | — | US | disclosed |
| US-11220577-B2 | Polyamide compound | TOYOTA BOSHOKU KABUSHIKI KAISHA (JP) | 2022-01-11 | — | — | US | disclosed |
| CN-108085021-B | Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal display element and reaction product | JSR株式会社 | 2021-06-08 | — | — | CN | disclosed |
| CN-106398721-B | Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, method for producing liquid crystal alignment film, polymer, and diamine | JSR株式会社 | 2020-11-06 | — | — | CN | disclosed |
| US-20200247950-A1 | POLYAMIDE COMPOUND | TOYOTA BOSHOKU KABUSHIKI KAISHA (JP) | 2020-08-06 | — | — | US | disclosed |
| US-20200247952-A1 | POLYAMIDE COMPOUND | TOYOTA BOSHOKU KABUSHIKI KAISHA (JP) | 2020-08-06 | — | — | US | disclosed |
| US-10450415-B2 | Polyamide compound, and method for producing same | TOYOTA BOSHOKU KABUSHIKI KAISHA (JP) | 2019-10-22 | — | — | US | disclosed |
| US-20180127544-A1 | POLYAMIDE COMPOUND, AND METHOD FOR PRODUCING SAME | TOYOTA BOSHOKU KABUSHIKI KAISHA (JP) | 2018-05-10 | — | — | US | disclosed |
| US-20150323837-A1 | LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR FABTICATING THE SAME | JSR CORPORATION (JP) | 2015-11-12 | — | — | US | disclosed |
| CN-102533281-A | Liquid crystal aligning agent, liquid crystal alignment film, method for forming the liquid crystal alignment film, and liquid crystal display device | JSR CORP | 2012-07-04 | — | — | CN | disclosed |
| CN-102382661-A | Liquid crystal orientation agent, liquid crystal orientation film, liquid crystal orientation display element, polyamic acid and polyimide | JSP KK | 2012-03-21 | — | — | CN | disclosed |
| US-20090298830-A1 | 4-Aryl-2-Amino-Pyrimidnes or 4-Aryl-2-Aminoalkyl-Pyrimidines as Jak-2 Modulators and Methods of Use | EXELIXIS, INC. (US) | 2009-12-03 | — | — | US | disclosed |
| US-20090298830-A1 | 4-Aryl-2-Amino-Pyrimidnes or 4-Aryl-2-Aminoalkyl-Pyrimidines as Jak-2 Modulators and Methods of Use | EXELIXIS, INC. (US) | 2009-12-03 | — | — | US | disclosed |
| US-20090298830-A1 | 4-Aryl-2-Amino-Pyrimidnes or 4-Aryl-2-Aminoalkyl-Pyrimidines as Jak-2 Modulators and Methods of Use | EXELIXIS, INC. (US) | 2009-12-03 | — | — | US | disclosed |
| CN-101421250-A | 4-aryl-2-amino-pyrimidines or 4-aryl-2-aminoalkyl-pyrimidines as jak-2 modulators and pharmaceutical compositions containing them | EXELIXIS INC (US) | 2009-04-29 | — | — | CN | disclosed |
| WO-2009017838-A2 | COMBINATIONS OF JAK-2 INHIBITORS AND OTHER AGENTS | EXELIXIS, INC. (US) | 2009-02-05 | — | — | WO | disclosed |
| WO-2008124085-A2 | METHODS OF USING COMBINATIONS OF MEK AND JAK-2 INHIBITORS | EXELIXIS, INC. (US) | 2008-10-16 | — | — | WO | disclosed |
| EP-1979329-A2 | 4-ARYL-2-AMINO-PYRIMIDINES OR 4-ARYL-2-AMINOALKYL-PYRIMIDINES AS JAK-2 MODULATORS AND METHODS OF USE | Exelixis, Inc. (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007089768-A2 | 4-ARYL-2-AMINO-PYRIMIDINES OR 4-ARYL-2-AMINOALKYL-PYRIMIDINES AS JAK-2 MODULATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | EXELIXIS, INC. (US) | 2007-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298830-A1 | 4-Aryl-2-Amino-Pyrimidnes or 4-Aryl-2-Aminoalkyl-Pyrimidines as Jak-2 Modulators and Methods of Use | JAK2, JAK1, JAK3 | MAPT 4630/4885SMN1; SMN2 4376/4885GAA 3430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.