SCHEMBL246323

SCHEMBL246323

COCCOc1ccc(C=O)cc1

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
MAPT P10636 3/20 0.61
HPGD P15428 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
LMNA P02545 1/20 0.61
CYP2A6 P11509 1/20 0.57
FDPS P14324 1/20 0.49
ALDH1A3 P47895 1/20 0.47
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
KDM4E B2RXH2 2/20 0.45
RECQL P46063 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7992010 0.94 ALDH1A1 (0.56) ALDH1A1MAPTHPGDSMN1; SMN2LMNA
SCHEMBL3210160 0.94 ALDH1A1 (0.56) ALDH1A1MAPTHPGDSMN1; SMN2LMNA
SCHEMBL3211688 0.94 ALDH1A1 (0.56) ALDH1A1MAPTHPGDSMN1; SMN2LMNA
SCHEMBL7989945 0.90 ALDH1A1 (0.64) ALDH1A1MAPTHPGDSMN1; SMN2LMNA
SCHEMBL3720061 0.90 ALDH1A1 (0.69) ALDH1A1MAPTHPGDSMN1; SMN2LMNA
SCHEMBL851166 0.89 ALDH1A1 (0.66) ALDH1A1MAPTHPGDSMN1; SMN2LMNA
SCHEMBL27256901 0.89 ALDH1A1 (0.62) ALDH1A1MAPTHPGDSMN1; SMN2LMNA
SCHEMBL19214413 0.88 ALDH1A1 (0.76) ALDH1A1MAPTHPGDSMN1; SMN2LMNA
SCHEMBL1524953 0.87 ALDH1A1 (0.52) ALDH1A1MAPTHPGDSMN1; SMN2LMNA
SCHEMBL18477951 0.84 ALDH1A1 (0.66) ALDH1A1MAPTHPGDSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102887862-A Method for synthesizing erlotinib LIANYUNGANG SHENGHE BIOTECHNOLOGY CO LTD 2013-01-23 CN claimed
US-20250170112-A1 ADENOSINE LIGANDS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS LUCY THERAPEUTICS, INC. 2025-05-29 US disclosed
EP-4069366-B1 ATM KINASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF CHDI FOUNDATION INC (US) 2025-03-19 EP disclosed
WO-2025038783-A1 ADENOSINE LIGANDS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS OR CHRONIC HEART FAILURE LUCY THERAPEUTICS, INC. (US) 2025-02-20 WO disclosed
WO-2025038781-A1 ADENOSINE LIGANDS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS OR CHRONIC HEART FAILURE LUCY THERAPEUTICS, INC. (US) 2025-02-20 WO disclosed
US-20250026749-A1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS GENZYME CORPORATION (US) 2025-01-23 US disclosed
EP-4479399-A1 ADENOSINE LIGANDS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS Lucy Therapeutics, Inc. (US) 2024-12-25 EP disclosed
CN-118546167-A Near infrared fluorescent dye and fluorescent composite material 复旦大学 2024-08-27 CN disclosed
US-12060349-B2 Glucosylceramide synthase inhibitors GENZYME CORPORATION (US) 2024-08-13 US disclosed
WO-2023158725-A1 ADENOSINE LIGANDS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS LUCY THERAPEUTICS, INC. (US) 2023-08-24 WO disclosed
US-6288061-B1 INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS WELFIDE CORPORATION (JP) 2001-09-11 US disclosed
US-20010014697-A1 Process for the preparation of 2-methoxyethoxy-benzenes and novel 2-methoxyethoxy-benzyl cyanides LANXESS DEUTSCHLAND GMBH (DE) 2001-08-16 US disclosed
EP-1123913-A2 Process for preparing 2-methoxyethoxybenzenes and new 2-methoxyethoxybenzyl cyanides BAYER AG (DE) 2001-08-16 EP disclosed
US-5840902-A REACTING PICOLINE WITH ALKYLENE OXIDE IN PRESENCE OF ACID IN WATER OR MIXTURE OF WATER AND POLAR SOLVENT BAYER AKTIENGESELLSCHAFT (DE) 1998-11-24 US disclosed
EP-0776888-A2 Process for the preparation of beta-Hydrosyalkylpicolinium salts and picolinium salts as intermediates for the prepation of cationic dyes BAYER AG (DE) 1997-06-04 EP disclosed
US-5422367-A A hormon inhibitors and for inhibiting the development of an estrogen-dependent tumor RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1995-06-06 US disclosed
US-5324736-A Diphenylcyclopropyl analogs as antiestrogenic and antitumor agents RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1994-06-28 US disclosed
US-5098903-A Halocyclopropanes BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 1992-03-24 US disclosed
US-4009208-A N,N'-HEPTAMETHYLENEBIS(4-METHOXYBENZAMIDE) STERLING DRUG INC. (US) 1977-02-22 US disclosed
US-3962219-A DISTYRYL-BENZOBISOXAZOLES BAYER AKTIENGESELLSCHAFT (DT) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12060349-B2 Glucosylceramide synthase inhibitors GBA1, GBA2, GALC ALDH1A1 2066/4885MAPT 3852/4885HPGD 1298/4885
US-20250026749-A1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS GBA1, GBA2, GAA ALDH1A1 2144/4885MAPT 4277/4885HPGD 1041/4885
US-20250170112-A1 ADENOSINE LIGANDS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS ADORA2A, ADORA1, PDE7A ALDH1A1 1355/4885MAPT 154/4885HPGD 1722/4885
US-20010014697-A1 Process for the preparation of 2-methoxyethoxy-benzenes and novel 2-methoxyethoxy-benzyl cyanides TET2, CYCS, TYR ALDH1A1 4144/4885MAPT 3465/4885HPGD 992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.