Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3210160 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL3211688 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL246323 | 0.94 | ALDH1A1 (0.61) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL8371513 | 0.91 | ALDH1A1 (0.59) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL1524953 | 0.89 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL3683901 | 0.86 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL27029040 | 0.86 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL9484385 | 0.86 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL10069015 | 0.85 | APP (0.58) | ALDH1A1MAPTHPGDKDM4ERECQL | |
| SCHEMBL3720061 | 0.85 | ALDH1A1 (0.69) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220106327-A1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-07 | — | — | US | disclosed |
| US-10851302-B2 | Metal organic liquid crystal dyes | GAUZY LTD. (IL) | 2020-12-01 | — | — | US | disclosed |
| EP-3209748-B1 | METAL ORGANIC LIQUID CRYSTAL DYES | GAUZY LTD (IL) | 2020-05-06 | — | — | EP | disclosed |
| US-20170355908-A1 | METAL ORGANIC LIQUID CRYSTAL DYES | GAUZY LTD. (IL) | 2017-12-14 | — | — | US | disclosed |
| US-20170355908-A1 | METAL ORGANIC LIQUID CRYSTAL DYES | GAUZY LTD. (IL) | 2017-12-14 | — | — | US | disclosed |
| EP-3209748-A1 | METAL ORGANIC LIQUID CRYSTAL DYES | Gauzy Ltd (IL) | 2017-08-30 | — | — | EP | disclosed |
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |
| US-5686610-A | Pyridyl piperazine compound | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0485636-B1 | INDOLE DERIVATIVE | TORAY INDUSTRIES (JP) | 1997-03-12 | — | — | EP | disclosed |
| US-5599930-A | Substituted indoles as anti-AIDS pharmaceuticals | THE UPJOHN COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| EP-0594702-B1 | SUBSTITUTED INDOLES AS ANTI-AIDS PHARMACEUTICALS | UPJOHN CO (US) | 1997-01-29 | — | — | EP | disclosed |
| EP-0735026-A1 | Method for the production of isoquinoline derivatives and their use as intermediates in the preparation of indole derivatives | TORAY INDUSTRIES, INC. (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-5539119-A | MULTISTAGE FORMATION BY OXIDATION, REDUCING A CARBAMATE TO FORM AN ENAMINE, FORMING AN OXIDE | TORAY INDUSTRIES, INC. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0594702-A1 | SUBSTITUTED INDOLES AS ANTI-AIDS PHARMACEUTICALS. | UPJOHN CO (US) | 1994-05-04 | — | — | EP | disclosed |
| US-5244904-A | Immunorepressant, analgesic | TORAY INDUSTRIES, INC. (JP) | 1993-09-14 | — | — | US | disclosed |
| WO-1993001181-A1 | SUBSTITUTED INDOLES AS ANTI-AIDS PHARMACEUTICALS | THE UPJOHN COMPANY (US) | 1993-01-21 | — | — | WO | disclosed |
| EP-0485636-A1 | INDOLE DERIVATIVE | TORAY INDUSTRIES, INC. (JP) | 1992-05-20 | — | — | EP | disclosed |
| EP-0150952-B1 | PHOTOPOLYMERIZABLE COMPOSITION | KURARAY CO., LTD. (JP) | 1989-08-30 | — | — | EP | disclosed |
| US-4668712-A | MONOMER, PHOTOINITIATOR, DENTAL FILLINGS | KURARAY CO., LTD. (JP) | 1987-05-26 | — | — | US | disclosed |
| EP-0150952-A2 | Photopolymerizable composition | KURARAY CO., LTD. (JP) | 1985-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220106327-A1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | APOL1, PNLIP, APOB | ALDH1A1 3889/4885MAPT 384/4885HPGD 2560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.