Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | CNR1 | P21554 | 6/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2456257 | 0.80 | MEN1 (0.47) | CNR2SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL2458690 | 0.78 | RAB9A (0.47) | SMN1; SMN2RAB9AHPGDNPC1TP53 | |
| SCHEMBL2459406 | 0.76 | RAB9A (0.45) | CNR2RAB9ANPC1ALDH1A1CNR1 | |
| SCHEMBL2458645 | 0.74 | SLC6A12 (0.46) | SMN1; SMN2RAB9AHPGDNPC1ALDH1A1 | |
| SCHEMBL2461640 | 0.73 | CNR2 (0.64) | CNR2SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL3802378 | 0.72 | RAB9A (0.49) | CNR2RAB9ANPC1ALDH1A1CNR1 | |
| SCHEMBL2464533 | 0.71 | DHODH (0.46) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL2460764 | 0.71 | NPC1 (0.54) | CNR2RAB9ANPC1CNR1MEN1 | |
| SCHEMBL17949724 | 0.70 | RAB9A (0.82) | CNR2SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL2459033 | 0.69 | SMYD3 (0.43) | RAB9AHPGDTP53MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534277-B1 | ACYLATED, HETEROARYL-CONDENSED CYCLOALKENYLAMINES AND THEIR USE AS PHARMACEUTICALS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-14 | — | — | EP | disclosed |