SCHEMBL24633440

SCHEMBL24633440

C/C=C/c1cc(OCc2ccccc2)cc(OCc2ccccc2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.60
CYP1A1 P04798 1/20 0.60
CYP19A1 P11511 1/20 0.60
LCK P06239 1/20 0.54
MAOB P27338 3/20 0.53
MAOA P21397 2/20 0.53
ALOX5 P09917 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
CCNB2 O95067 1/20 0.51
CDK1 P06493 1/20 0.51
CDK4 P11802 1/20 0.51
CCNB1 P14635 1/20 0.51
CCND1 P24385 1/20 0.51
CCNB3 Q8WWL7 1/20 0.51
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
PKM P14618 1/20 0.50
AKR1C3 P42330 1/20 0.48
AKR1C2 P52895 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9434794 0.87 LCK (0.72) LCKMAOBMAOAALOX5CCNB2
SCHEMBL9434803 0.87 LCK (0.72) LCKMAOBMAOAALOX5CCNB2
SCHEMBL28441803 0.86 CYP1A2 (0.73) CYP1A2CYP1A1CYP19A1LCKMAOB
SCHEMBL11896472 0.84 LCK (0.64) CYP1A2CYP1A1CYP19A1LCKMAOB
SCHEMBL14419745 0.84 LCK (0.64) CYP1A2CYP1A1CYP19A1LCKMAOB
SCHEMBL24633372 0.83 CYP1A2 (0.57) CYP1A2CYP1A1CYP19A1LCKMAOB
SCHEMBL3650797 0.83 LCK (0.77) CYP1A2CYP1A1CYP19A1LCKMAOB
SCHEMBL6308482 0.83 LCK (0.77) CYP1A2CYP1A1CYP19A1LCKMAOB
SCHEMBL3650792 0.83 LCK (0.77) CYP1A2CYP1A1CYP19A1LCKMAOB
SCHEMBL19728207 0.82 CYP1A1 (0.68) CYP1A2CYP1A1CYP19A1LCKMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322654-A1 CANNABINOID DERIVATIVES AND THEIR USE DEMEETRA AGBIO, INC. 2023-10-12 US disclosed
US-20230248748-A1 CANNABINOID DERIVATIVES AND THEIR USE DEMEETRA AGBIO, INC. 2023-08-10 US disclosed
US-20230059087-A1 CANNABIDIOL DERIVATIVES, PREPARATION METHOD THEREOF AND USE THEREOF CHENGDU BAIYU PHARMACEUTICAL CO., LTD. (CN) 2023-02-23 US disclosed
WO-2023015253-A1 CANNABINOID DERIVATIVES AND THEIR USE DEMEETRA AGBIO, INC. (US) 2023-02-09 WO disclosed
EP-4089084-A1 CANNABIDIOL DERIVATIVE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF Chengdu Baiyu Pharmaceutical Co., Ltd. (CN) 2022-11-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230248748-A1 CANNABINOID DERIVATIVES AND THEIR USE CNR1, CNR2, FAAH CYP1A2 602/4885CYP1A1 440/4885CYP19A1 2362/4885
US-20230322654-A1 CANNABINOID DERIVATIVES AND THEIR USE CNR1, CNR2, FAAH CYP1A2 602/4885CYP1A1 440/4885CYP19A1 2362/4885
US-20230059087-A1 CANNABIDIOL DERIVATIVES, PREPARATION METHOD THEREOF AND USE THEREOF CNR1, CNR2, UGT2B7 CYP1A2 20/4885CYP1A1 49/4885CYP19A1 63/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.