SCHEMBL3650792

SCHEMBL3650792

C(=C/c1cc(OCc2ccccc2)cc(OCc2ccccc2)c1)\c1ccc(OCc2ccccc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.77
CYP1A2 P05177 2/20 0.74
CYP1A1 P04798 1/20 0.74
CYP19A1 P11511 1/20 0.74
GSK3B P49841 3/20 0.60
BACE1 P56817 3/20 0.60
PPARG P37231 3/20 0.59
PPARA Q07869 2/20 0.59
FFAR1 O14842 1/20 0.59
PPARD Q03181 1/20 0.59
RAB9A P51151 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
NPC1 O15118 1/20 0.56
ALOX5 P09917 1/20 0.56
SLC5A1 P13866 1/20 0.55
SLC5A2 P31639 1/20 0.55
LMNA P02545 1/20 0.55
PTGS1 P23219 1/20 0.55
SLC6A2 P23975 1/20 0.55
CYP2C19 P33261 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6308482 1.00 LCK (0.77) LCKCYP1A2CYP1A1CYP19A1GSK3B
SCHEMBL3650797 1.00 LCK (0.77) LCKCYP1A2CYP1A1CYP19A1GSK3B
SCHEMBL6796518 0.95 LCK (0.74) LCKCYP1A2CYP1A1CYP19A1GSK3B
SCHEMBL28441803 0.93 CYP1A2 (0.73) LCKCYP1A2CYP1A1CYP19A1GSK3B
SCHEMBL20024692 0.91 LCK (0.77) LCKCYP1A2CYP1A1CYP19A1GSK3B
SCHEMBL14786203 0.91 LCK (0.77) LCKCYP1A2CYP1A1CYP19A1GSK3B
SCHEMBL1975680 0.91 LCK (0.68) LCKCYP1A2CYP1A1CYP19A1PPARG
SCHEMBL1975681 0.91 LCK (0.68) LCKCYP1A2CYP1A1CYP19A1PPARG
SCHEMBL8913578 0.89 LCK (0.81) LCKCYP1A2CYP1A1CYP19A1GSK3B
SCHEMBL8913590 0.89 LCK (0.81) LCKCYP1A2CYP1A1CYP19A1GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1466884-A1 Process for the preparation of resveratrol and its uses Sochinaz SA (CH) 2004-10-13 EP claimed
WO-2001060774-A1 SYNTHESIS OF RESVERATROL BRIGHAM YOUNG UNIVERSITY (US) 2001-08-23 WO claimed
CN-106336347-B New method for synthesizing hydroxystilbenes 中国科学院成都有机化学有限公司 2020-08-18 CN disclosed
US-20170362152-A1 NOVEL 1,2-DIPHENYLETHYLENE GLYCOL COMPOUNDS FOR COMBATING AGING OF THE SKIN, AND COSMETIC USE THEREOF L'OREAL (FR) 2017-12-21 US disclosed
EP-2205544-B1 PROCESS FOR THE SYNTHESIS OF POLYHYDROXYSTILBENE COMPOUNDS CLARIANT SPECIALTY FINE CHEM F (FR) 2013-11-06 EP disclosed
US-8399714-B2 Process for the synthesis of polyhydroxystilbene compounds CLARIANT SPECIALITY FINE CHEMICALS (FRANCE) (FR) 2013-03-19 US disclosed
US-20100324342-A1 PROCESS FOR THE SYNTHESIS OF POLYHYDROXYSTILBENE COMPOUNDS CLARIANT SPECIALTY FINE CHEMICALS (FRANCE) (FR) 2010-12-23 US disclosed
EP-2205544-A1 PROCESS FOR THE SYNTHESIS OF POLYHYDROXYSTILBENE COMPOUNDS Clariant Specialty Fine Chemicals (France) (FR) 2010-07-14 EP disclosed
WO-2009043761-A1 PROCESS FOR THE SYNTHESIS OF POLYHYDROXYSTILBENE COMPOUNDS CLARIANT SPECIALTY FINE CHEMICALS (FRANCE) (FR) 2009-04-09 WO disclosed
US-6844471-B2 Method for the conversion of a Z-isomer into E-isomer ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) 2005-01-18 US disclosed
EP-1466884-A1 Process for the preparation of resveratrol and its uses Sochinaz SA (CH) 2004-10-13 EP disclosed
WO-2004009539-A2 METHOD FOR THE CONVERSION OF A Z-ISOMER INTO E-ISOMER ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) 2004-01-29 WO disclosed
US-20040015020-A1 Method for the conversion of a Z-isomer into E-isomer ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) 2004-01-22 US disclosed
WO-2003094833-A2 A NEW STEREOSELECTIVE ROUTE TO PRODUCE TRIS-O-SUBSTITUTED-(E)-( 3,5-DIHYDROXYPHENYL)-2-(4- HYDROXYPHENYL)ETHENE ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) 2003-11-20 WO disclosed
US-6552213-B1 Oxidation and halogenation of such as 3,4',5-tribenzyloxy-dibenzylsulfide; reductive dehalogenation desulfonation; hydrolysis ORCHID CHEMICALS & PHARMACEUTICALS LIMITED, INDIA (IN) 2003-04-22 US disclosed
WO-2001060774-A1 SYNTHESIS OF RESVERATROL BRIGHAM YOUNG UNIVERSITY (US) 2001-08-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040015020-A1 Method for the conversion of a Z-isomer into E-isomer ECH1, CYP1A1, KEAP1 LCK 4680/4885CYP1A2 106/4885CYP1A1 2/4885
US-20100324342-A1 PROCESS FOR THE SYNTHESIS OF POLYHYDROXYSTILBENE COMPOUNDS ASH2L, ASPH, HRH1 LCK 2457/4885CYP1A2 200/4885CYP1A1 91/4885
US-20170362152-A1 NOVEL 1,2-DIPHENYLETHYLENE GLYCOL COMPOUNDS FOR COMBATING AGING OF THE SKIN, AND COSMETIC USE THEREOF GLA, DSG1, GPX1 LCK 3536/4885CYP1A2 1230/4885CYP1A1 665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.