SCHEMBL9434794

SCHEMBL9434794

C/C=C/c1cccc(OCc2ccccc2)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.72
CCNB2 O95067 1/20 0.68
CDK1 P06493 1/20 0.68
CDK4 P11802 1/20 0.68
CCNB1 P14635 1/20 0.68
CCND1 P24385 1/20 0.68
CCNB3 Q8WWL7 1/20 0.68
MAOB P27338 10/20 0.67
MAOA P21397 6/20 0.67
KDM4E B2RXH2 1/20 0.67
ALDH1A1 P00352 1/20 0.67
PKM P14618 1/20 0.67
TLR4 O00206 1/20 0.63
TLR2 O60603 1/20 0.63
BCHE P06276 2/20 0.54
ALOX5 P09917 1/20 0.53
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CYP4F2 P78329 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9434803 1.00 LCK (0.72) LCKCCNB2CDK1CDK4CCNB1
SCHEMBL24633440 0.87 CYP1A2 (0.60) LCKCCNB2CDK1CDK4CCNB1
SCHEMBL5545087 0.87 MAOB (0.71) LCKCCNB2CDK1CDK4CCNB1
SCHEMBL17821808 0.85 LCK (0.74) LCKCCNB2CDK1CDK4CCNB1
SCHEMBL17821810 0.85 LCK (0.74) LCKCCNB2CDK1CDK4CCNB1
SCHEMBL15008643 0.83 LCK (0.59) LCKCCNB2CDK1CDK4CCNB1
SCHEMBL15008640 0.83 LCK (0.59) LCKCCNB2CDK1CDK4CCNB1
SCHEMBL15008639 0.83 LCK (0.59) LCKCCNB2CDK1CDK4CCNB1
SCHEMBL27299988 0.83 LCK (0.67) LCKCCNB2CDK1CDK4CCNB1
SCHEMBL14691654 0.83 LCK (0.70) LCKCCNB2CDK1CDK4CCNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013090161-A1 STEREOSELECTIVE SYNTHESIS OF TAPENTADOL AND ITS SALTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-06-20 WO claimed
EP-3423433-B1 SULFAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES BIO PHARM SOLUTIONS CO LTD (KR) 2025-12-17 EP disclosed
CN-109071424-B Sulfamate derivative compound, preparation method and application thereof 生物药品解决方案有限公司 2022-01-14 CN disclosed
US-10351519-B2 Sulfamate derivative compounds, processes for preparing them and their uses BIO-PHARM SOLUTIONS CO., LTD. (KR) 2019-07-16 US disclosed
US-10351519-B2 Sulfamate derivative compounds, processes for preparing them and their uses BIO-PHARM SOLUTIONS CO., LTD. (KR) 2019-07-16 US disclosed
EP-3423433-A1 SULFAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES Bio-Pharm Solutions Co., Ltd. (KR) 2019-01-09 EP disclosed
WO-2012089181-A1 O-SUBSTITUTED (2R,3R)-3-(3-HYDROXYPHENYL)-2-METHYL-4-PENTENOIC ACIDS AND A METHOD OF OBTAINING THE SAME ZENTIVA, K.S. (CZ) 2012-07-05 WO disclosed
WO-1994000432-A1 ANORECTIC EPINEPHRINE DERIVATIVES THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1994-01-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351519-B2 Sulfamate derivative compounds, processes for preparing them and their uses STS, SULT2A1, SULT1A1 LCK 2422/4885CCNB2 4105/4885CDK1 3516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.