Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22077974 | 0.81 | ACHE (0.36) | GABRA2GABRB2AR | |
| SCHEMBL22924927 | 0.73 | — | — | |
| SCHEMBL18367588 | 0.69 | GABRA2 (0.36) | GABRA2GABRB2 | |
| SCHEMBL25009052 | 0.68 | ACHE (0.35) | GABRA2GABRB2AR | |
| SCHEMBL20215059 | 0.68 | GABRA2 (0.35) | GABRA2GABRB2 | |
| SCHEMBL9537466 | 0.66 | ALDH1A1 (0.34) | GABRA2GABRB2AR | |
| SCHEMBL15255587 | 0.66 | AR (0.36) | GABRA2GABRB2AR | |
| SCHEMBL20462216 | 0.66 | — | — | |
| SCHEMBL18623671 | 0.65 | AR (0.39) | GABRA2GABRB2AR | |
| SCHEMBL12985093 | 0.63 | AR (0.33) | GABRA2GABRB2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022222960-A1 | FXIA INHIBITOR AND PHARMACEUTICAL COMPOSITION, PREPARATION METHOD AND USE THEREOF | 上海美悦生物科技发展有限公司 | 2022-10-27 | — | — | WO | disclosed |