Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24633651 | 0.82 | RAB9A (0.31) | KDM4E | |
| SCHEMBL24633603 | 0.71 | PTPN1 (0.35) | — | |
| SCHEMBL24633654 | 0.69 | — | — | |
| SCHEMBL20448940 | 0.67 | GAA (0.46) | KMT2A | |
| SCHEMBL2263489 | 0.66 | NR1I2 (0.42) | KMT2A | |
| SCHEMBL5704306 | 0.63 | ALDH1A1 (0.44) | KMT2A | |
| SCHEMBL23732247 | 0.61 | PARP1 (0.35) | — | |
| SCHEMBL24633627 | 0.59 | CYP2A6 (0.43) | KMT2AKDM4E | |
| SCHEMBL8410387 | 0.59 | SLC6A4 (0.36) | KMT2A | |
| SCHEMBL5749794 | 0.59 | ESR1 (0.58) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240830-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | BRIDGE MEDICINES (US) | 2022-11-17 | — | — | WO | disclosed |