Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23963002 | 0.84 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DTDP1 | |
| SCHEMBL14330440 | 0.78 | CYP19A1 (0.45) | PDE4DCYP3A4NPC1RAB9AMAPT | |
| SCHEMBL9206685 | 0.77 | HSD17B3 (0.55) | TDP1SMN1; SMN2THRBNPC1USP2 | |
| SCHEMBL21758843 | 0.77 | MEN1 (0.30) | TDP1MEN1KMT2A | |
| SCHEMBL21415504 | 0.76 | F2 (0.44) | TDP1SMN1; SMN2CYP3A4ALOX15TP53 | |
| SCHEMBL22454375 | 0.74 | CA12 (0.46) | MAPTKDM4EGAAHSD17B3L3MBTL1 | |
| SCHEMBL20619804 | 0.73 | MAOA (0.44) | ALDH1A1HPGDHTTTSHR | |
| SCHEMBL28930609 | 0.73 | HSD17B3 (0.33) | SMN1; SMN2HPGDHSD17B3ESR1ESR2 | |
| SCHEMBL20157094 | 0.73 | HSD17B3 (0.33) | PDE4DCYP3A4THRBHSD17B10MAPT | |
| SCHEMBL11694880 | 0.73 | TDP1 (0.42) | PDE4APDE4BPDE4CPDE4DTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240830-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | BRIDGE MEDICINES (US) | 2022-11-17 | — | — | WO | disclosed |