Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29431604 | 0.96 | ADH1B (0.43) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL491435 | 0.96 | — | — | |
| SCHEMBL491426 | 0.96 | NOS1 (0.39) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL11006113 | 0.92 | CHRM5 (0.43) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL1524658 | 0.92 | CHRM5 (0.43) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL23070439 | 0.92 | CHRM5 (0.43) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL6533680 | 0.92 | CHRM5 (0.43) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL6532715 | 0.92 | CHRM5 (0.43) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL187659 | 0.92 | CHRM5 (0.43) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL2708909 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004523599-A | — | — | 2004-08-05 | — | — | JP | claimed |
| EP-1353961-A2 | (CYCLOALKYL)METHYL SILANES AS EXTERNAL DONORS FOR POLYOLEFIN CATALYSTS | ENGELHARD CORPORATION (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002016444-A2 | (CYCLOAKYL)METHYL SILANES AS EXTERNAL DONORS FOR POLYOLEFIN CATALYSTS | ENGELHARD CORPORATION (US) | 2002-02-28 | — | — | WO | claimed |
| US-20200270260-A1 | FUSED PYRIMIDINE COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2020-08-27 | — | — | US | disclosed |
| WO-2011110367-A2 | METHOD OF SCREENING FOR HTRA PROTEASE INHIBITORS USEFUL FOR PROPHYLAXIS AND THERAPY OF A BACTERIAL INFECTION | PAUL-EHRLICH-INSTITUT (DE) | 2011-09-15 | — | — | WO | disclosed |
| EP-2365091-A1 | Method of screening for HtrA protease inhibitors useful for prophylaxis and therapy of a bacterial infection | Paul-Ehrlich-Institut (DE) | 2011-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200270260-A1 | FUSED PYRIMIDINE COMPOUND OR SALT THEREOF | RET, RB1, MECP2 | ADH1B 1409/4885ADH1C 3186/4885ADH1A 3568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.