Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15110954 | 0.78 | TRPV4 (0.39) | TRPV4 | |
| SCHEMBL13765786 | 0.78 | LOXL2 (0.31) | LOXL2 | |
| SCHEMBL30329152 | 0.78 | TRPV4 (0.39) | TRPV4 | |
| SCHEMBL7995882 | 0.78 | TRPV4 (0.39) | TRPV4 | |
| SCHEMBL10272802 | 0.78 | TRPV4 (0.39) | TRPV4 | |
| SCHEMBL13527768 | 0.78 | LOXL2 (0.32) | LOXL2 | |
| SCHEMBL7999361 | 0.76 | TLR7 (0.33) | LOXL2LOXTRPV4 | |
| SCHEMBL16647905 | 0.75 | TRPA1 (0.42) | LOXL2LOX | |
| SCHEMBL14947798 | 0.75 | TRPV4 (0.36) | TRPV4 | |
| SCHEMBL15530614 | 0.75 | NAMPT (0.47) | LOXL2TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4079725-A1 | N-CARBOXAMIDOPYRAZOLINE DERIVATIVE SERVING AS P2X3 RECEPTOR ANTAGONIST AND APPLICATIONS | Hangzhou Westan Pharmaceutical Technology Co., Ltd. (CN) | 2022-10-26 | — | — | EP | disclosed |