Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LCK | P06239 | 4/20 | 0.33 |
| ▸ | C1S | P09871 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL439463 | 0.99 | MAPT (0.35) | MAPTTP53SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29821277 | 0.68 | HSD17B10 (0.49) | MAPTSMN1; SMN2KMT2AGLAGAA | |
| SCHEMBL1602168 | 0.68 | HSD17B10 (0.49) | MAPTSMN1; SMN2KMT2AGLAGAA | |
| SCHEMBL21642536 | 0.65 | SMN1; SMN2 (0.45) | TP53SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL9092404 | 0.63 | HRH4 (0.43) | HRH4HRH3 | |
| SCHEMBL25428682 | 0.59 | TBK1 (0.36) | KMT2AMEN1GLAGAA | |
| SCHEMBL9039325 | 0.59 | ALDH1A1 (0.50) | MAPTSMN1; SMN2KMT2AGAAHRH4 | |
| SCHEMBL21541915 | 0.57 | — | — | |
| SCHEMBL30388793 | 0.56 | HRH4 (0.44) | MAPTSMN1; SMN2KMT2AMEN1HRH4 | |
| SCHEMBL5866936 | 0.56 | KHK (0.46) | MAPTSMN1; SMN2KMT2AMEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011112731-A2 | HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2011-09-15 | — | — | WO | disclosed |