Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | BCL9 | O00512 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10938949 | 0.87 | MAPT (0.62) | MAPTBCL9CTNNB1ALDH1A1RAB9A | |
| SCHEMBL6659906 | 0.84 | BCL9 (0.64) | MAPTBCL9CTNNB1ALDH1A1RAB9A | |
| SCHEMBL28840398 | 0.83 | TBXAS1 (0.55) | ALDH1A1NAMPTKMT2ACYP3A4CYP2C9 | |
| Phenyl Propionic Acid SCHEMBL11756556 | 0.81 | ALDH1A1 (0.60) | MAPTBCL9CTNNB1ALDH1A1RAB9A | |
| SCHEMBL4489396 | 0.81 | NAMPT (0.54) | MAPTALDH1A1NAMPTPOLBHTT | |
| SCHEMBL1126283 | 0.80 | MAPT (0.60) | MAPTALDH1A1RAB9ANPSR1NAMPT | |
| SCHEMBL1568902 | 0.79 | NAMPT (0.65) | MAPTALDH1A1NAMPTPOLBHTT | |
| SCHEMBL28060070 | 0.79 | BCL9 (0.60) | MAPTBCL9CTNNB1ALDH1A1NPSR1 | |
| SCHEMBL957930 | 0.78 | BCL9 (0.81) | MAPTBCL9CTNNB1ALDH1A1RAB9A | |
| SCHEMBL12715327 | 0.78 | BCL9 (0.62) | MAPTBCL9CTNNB1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377468-A | 2, 6-dichlorophenyl ester compound and application thereof | 融合制药公司 | 2024-01-09 | — | — | CN | disclosed |
| WO-2022251612-A1 | 2,6-DICHLOROPHENYL ESTER COMPOUNDS AND USE THEREOF | Fusion Pharmaceuticals Inc. (CA) | 2022-12-01 | — | — | WO | disclosed |