Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 4/20 | 0.49 |
| ▸ | CES1 | P23141 | 4/20 | 0.49 |
| ▸ | RARB | P10826 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL29233380 | 1.00 | TSHR (0.52) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL2007986 | 0.95 | CES2 (0.50) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28107042 | 0.93 | CES2 (0.51) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27642010 | 0.93 | CES2 (0.51) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28954695 | 0.93 | CES2 (0.51) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27624637 | 0.93 | CES2 (0.51) | TSHRDAONAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL29199831 | 0.92 | RARB (0.53) | TSHRRARBTP53PLA2G4B | |
| Benzoic Acid SCHEMBL27622982 | 0.90 | CES2 (0.49) | TSHRDAONAPRTCES2CES1 | |
| Isophthalic Acid SCHEMBL30402759 | 0.89 | KMT2A (0.49) | PLA2G4B | |
| Benzoic Acid SCHEMBL17391496 | 0.89 | TSHR (0.56) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290623-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290624-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290625-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-114478846-B | Carrier of catalyst with olefin polymerization catalyzing function, preparation method and application thereof, olefin polymerization catalyst and application thereof | 中国石油化工股份有限公司 | 2023-09-08 | — | — | CN | claimed |
| CN-115975084-A | Catalyst component for olefin polymerization, catalyst and application | 中国石油化工股份有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-104204001-A | Catalyst component for the polymerization of olefins | SAUDI BASIC INDUSTRY CORP | 2014-12-10 | — | — | CN | claimed |
| CN-102432459-B | Purifying method of dihydroxy alcohol ester compound | CHINA PETROLEUM & CHEMICAL | 2014-12-03 | — | — | CN | claimed |
| CN-102187000-B | Metal extractant reagents having increased resistance to degradation | CYTEC TECH CORP | 2014-08-27 | — | — | CN | claimed |
| CN-103665205-A | Catalyst component applied to olefin polymerization, preparation method thereof, catalyst for olefin polymerization and application of catalyst | CHINA PETROLEUM & CHEMICAL | 2014-03-26 | — | — | CN | claimed |
| CN-103012626-A | Olefin polymerization catalyst ingredient, preparation method of the olefin polymerization catalyst ingredient, catalyst system, use of the catalyst system, and olefin polymerization method | CHINA PETROLEUM & CHEMICAL | 2013-04-03 | — | — | CN | claimed |
| CN-103012631-A | Preparation method of propylene polymer | CHINA PETROLEUM & CHEMICAL | 2013-04-03 | — | — | CN | claimed |
| CN-103012625-A | Olefin polymerization catalyst ingredient, preparation method and use of the olefin polymerization catalyst ingredient, catalyst system, use of the catalyst system, and olefin polymerization method | CHINA PETROLEUM & CHEMICAL | 2013-04-03 | — | — | CN | claimed |
| CN-101643519-B | Catalyst component used for propene polymerization and catalyst | SINOPEC CORP. (CN) | 2011-11-30 | — | — | CN | claimed |
| CN-101643520-B | Catalyst for propene polymerization | SINOPEC CORP. (CN) | 2011-11-02 | — | — | CN | claimed |
| CN-101643520-A | Catalyst for propene polymerization | CHINA PETROLEUM & CHEMICAL | 2010-02-10 | — | — | CN | claimed |
| CN-101643519-A | Catalyst component used for propene polymerization and catalyst | CHINA PETROLEUM & CHEMICAL | 2010-02-10 | — | — | CN | claimed |
| CN-118290624-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118290625-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-1453298-A | Catalyst for olefine polymerizing reaction and its components | CHINA PETROCHEMICAL CORP (CN) | 2003-11-05 | — | — | CN | disclosed |
| WO-1998006788-A1 | BLACK INK JET INK COMPOSITION | REXAM GRAPHICS INC. (US) | 1998-02-19 | — | — | WO | disclosed |