Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28107042 | 0.98 | CES2 (0.51) | CES2CES1TSHRDAONAPRT | |
| Benzoic Acid SCHEMBL27624637 | 0.98 | CES2 (0.51) | CES2CES1TSHRDAONAPRT | |
| Benzoic Acid SCHEMBL28954695 | 0.98 | CES2 (0.51) | CES2CES1TSHRDAONAPRT | |
| Benzoic Acid SCHEMBL27642010 | 0.98 | CES2 (0.51) | CES2CES1TSHRDAONAPRT | |
| Benzoic Acid SCHEMBL27622982 | 0.95 | CES2 (0.49) | CES2CES1TSHRDAONAPRT | |
| Benzoic Acid SCHEMBL2463701 | 0.95 | TSHR (0.52) | CES2CES1TSHRDAONAPRT | |
| Benzoic Acid SCHEMBL29233380 | 0.95 | TSHR (0.52) | CES2CES1TSHRDAONAPRT | |
| Terephthalic Acid SCHEMBL8840756 | 0.93 | RARB (0.54) | TSHRRARBTP53PLA2G4BALDH1A1 | |
| Terephthalic Acid SCHEMBL11562692 | 0.93 | RARB (0.54) | TSHRRARBTP53PLA2G4BALDH1A1 | |
| Terephthalic Acid SCHEMBL29199869 | 0.91 | TP53 (0.57) | TSHRRARBTP53PLA2G4BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478846-A | Carrier of catalyst with function of catalyzing olefin polymerization, preparation method and application of carrier, olefin polymerization catalyst and application of olefin polymerization catalyst | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| WO-2011071674-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2011-06-16 | — | — | WO | claimed |
| US-20100113664-A1 | Asymmetric Cyclic Diester Compounds | FERRO CORPORATION (US) | 2010-05-06 | — | — | US | claimed |
| EP-1395232-B1 | COSMETIC COMPOSITION FOR NAILS, FREE OF PHTHALATES, CAMPHOR AND AROMATIC SOLVENT | FIABILA (FR) | 2006-10-18 | — | — | EP | claimed |
| US-20030152535-A1 | Cosmetic composition for nails, free of phthalates, camphor and aromatic solvent | FIABILA (FR) | 2003-08-14 | — | — | US | claimed |
| CN-114478846-A | Carrier of catalyst with function of catalyzing olefin polymerization, preparation method and application of carrier, olefin polymerization catalyst and application of olefin polymerization catalyst | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-104558282-B | Catalyst component used for olefin polymerization and preparation method thereof as well as catalyst used for olefin polymerization and application | 中国石油化工股份有限公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-103154050-B | Olefin polymerization process | 巴塞尔聚烯烃意大利有限责任公司 | 2016-11-16 | — | — | CN | disclosed |
| US-8679465-B2 | Cosmetic composition for nails, free of phthalates, camphor and aromatic solvent | FIABILA (FR) | 2014-03-25 | — | — | US | disclosed |
| WO-2011071674-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2011-06-16 | — | — | WO | disclosed |
| US-20100113664-A1 | Asymmetric Cyclic Diester Compounds | FERRO CORPORATION (US) | 2010-05-06 | — | — | US | disclosed |
| US-7388061-B2 | Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-06-17 | — | — | US | disclosed |
| US-20050239636-A1 | Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2005-10-27 | — | — | US | disclosed |
| US-20030152535-A1 | Cosmetic composition for nails, free of phthalates, camphor and aromatic solvent | FIABILA (FR) | 2003-08-14 | — | — | US | disclosed |
| EP-0034337-B1 | A PROCESS FOR THE OPTICAL RESOLUTION OF A RACEMIC MIXTURE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1984-10-24 | — | — | EP | disclosed |
| US-4259225-A | STORAGE STABILITY | DAINIPPON INK & CHEMICALS, INC. (JP) | 1981-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030152535-A1 | Cosmetic composition for nails, free of phthalates, camphor and aromatic solvent | PIK3C3, POLR1C, CECR2 | CES2 759/4885CES1 2703/4885TSHR 1276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.