Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CRAT | P43155 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23138664 | 0.85 | CRAT (0.35) | MGAMGAASIMGAM2ACACB | |
| SCHEMBL11126995 | 0.84 | MGAM (0.50) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL21327975 | 0.81 | MGAM (0.46) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL1405748 | 0.78 | MGAM (0.43) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL11126678 | 0.78 | MGAM (0.43) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL11126682 | 0.78 | MGAM (0.43) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL4156137 | 0.77 | CNR2 (0.42) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL592891 | 0.75 | PLA2G2C (0.53) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL18946197 | 0.75 | CAD (0.40) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL1071728 | 0.75 | CAD (0.40) | MGAMGAASIMGAM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220323415-A1 | L-PAG DERIVATIVES FOR TREATMENT OF SLEEP DISORDERED BREATHING (SDB) | IIT RESEARCH INSTITUTE | 2022-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220323415-A1 | L-PAG DERIVATIVES FOR TREATMENT OF SLEEP DISORDERED BREATHING (SDB) | GLRB, GABRB3, GABRB1 | MGAM 3436/4885GAA 1415/4885SI 2929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.