Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29685778 | 0.84 | SMN1; SMN2 (0.49) | IL1BHDAC1HDAC6HDAC5SMN1; SMN2 | |
| SCHEMBL16705085 | 0.84 | SMN1; SMN2 (0.49) | IL1BHDAC1HDAC6HDAC5SMN1; SMN2 | |
| SCHEMBL17562270 | 0.74 | HDAC1 (0.36) | IL1BHDAC1HDAC6HDAC5SMN1; SMN2 | |
| SCHEMBL13576998 | 0.71 | HTT (0.46) | HDAC1HDAC6HDAC5SMN1; SMN2NPC1 | |
| SCHEMBL29761634 | 0.71 | HTT (0.46) | HDAC1HDAC6HDAC5SMN1; SMN2NPC1 | |
| SCHEMBL13750579 | 0.70 | NPC1 (0.36) | HDAC1HDAC6HDAC5NPC1RECQL | |
| SCHEMBL17562268 | 0.70 | MEN1 (0.34) | HDAC1HDAC6HDAC5SMN1; SMN2L3MBTL1 | |
| SCHEMBL24244792 | 0.67 | MEN1 (0.35) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL19624156 | 0.67 | LMNA (0.41) | HDAC1HDAC6HDAC5SMN1; SMN2NPC1 | |
| SCHEMBL31445352 | 0.67 | KDM4E (0.42) | HDAC1HDAC6HDAC5SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022208370-A1 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | PI INDUSTRIES LTD. (IN) | 2022-10-06 | — | — | WO | disclosed |