Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | MASP2 | O00187 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | ESRRG | P62508 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201867 | 0.73 | CYP19A1 (0.48) | CYP19A1ESR1ESR2LMNACYP1A2 | |
| SCHEMBL9321897 | 0.72 | ESR1 (0.69) | CYP19A1ESR1ESR2LMNACYP1A2 | |
| SCHEMBL9321894 | 0.72 | ESR1 (0.69) | CYP19A1ESR1ESR2LMNACYP1A2 | |
| SCHEMBL10638510 | 0.69 | LMNA (0.46) | CYP19A1ESR1ESR2LMNACYP1A2 | |
| SCHEMBL1178330 | 0.69 | LMNA (0.46) | CYP19A1ESR1ESR2LMNACYP1A2 | |
| SCHEMBL3264307 | 0.65 | CYP19A1 (0.58) | CYP19A1ESR1ESR2LMNACYP1A2 | |
| SCHEMBL19257842 | 0.65 | MAPK1 (0.41) | LMNANPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL19400486 | 0.64 | LMNA (0.48) | CYP19A1ESR1ESR2LMNACYP1A2 | |
| SCHEMBL27470926 | 0.63 | CYP19A1 (0.56) | CYP19A1ESR1ESR2LMNACYP1A2 | |
| SCHEMBL7173100 | 0.63 | ATM (0.36) | ESR1ESR2CYP1A2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3500252-B1 | MODIFIED PEPTIDES FOR USE IN TREATING NEURODEGENERATIVE DISORDERS | NEURO BIO LTD (GB) | 2022-11-02 | — | — | EP | disclosed |