SCHEMBL3264307

SCHEMBL3264307

CC[C](CC)c1ccc(N)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 5/20 0.58
ESR1 P03372 3/20 0.50
ESR2 Q92731 3/20 0.50
CYP3A4 P08684 4/20 0.48
LMNA P02545 3/20 0.48
CYP1A2 P05177 2/20 0.48
MAOA P21397 2/20 0.48
MASP2 O00187 1/20 0.44
PLAU P00749 1/20 0.44
THPO P40225 1/20 0.44
TSHR P16473 5/20 0.42
CYP2C19 P33261 2/20 0.42
CYP2C9 P11712 1/20 0.42
PDE4D Q08499 1/20 0.42
F2 P00734 1/20 0.42
PRSS1 P07477 1/20 0.42
APEX1 P27695 1/20 0.42
PRSS3 P35030 1/20 0.42
MAPT P10636 2/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27470926 0.77 CYP19A1 (0.56) CYP19A1ESR1ESR2CYP3A4LMNA
SCHEMBL3989195 0.76 ALDH1A1 (0.48) LMNAMEN1KMT2AALDH1A1TDP1
SCHEMBL11698205 0.75 CYP19A1 (0.54) CYP19A1ESR1ESR2CYP3A4LMNA
SCHEMBL221282 0.75 MAPT (0.57) CYP19A1ESR1ESR2CYP3A4LMNA
SCHEMBL4884033 0.74 HTR7 (0.47) LMNAALDH1A1NPC1RAB9AACHE
SCHEMBL3369640 0.74 HTT (0.48) CYP3A4CYP1A2CYP2C19CYP2C9MAPT
Alcohol SCHEMBL10901320 0.74 MEN1 (0.57) CYP19A1ESR1ESR2CYP3A4LMNA
SCHEMBL28193845 0.73 CYP19A1 (0.58) CYP19A1ESR1ESR2CYP3A4LMNA
SCHEMBL18863007 0.73 CYP19A1 (1.00) CYP19A1ESR1ESR2CYP3A4LMNA
SCHEMBL28143278 0.73 CYP19A1 (0.69) CYP19A1ESR1ESR2CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1712601-B1 Phase change inks XEROX CORP (US) 2010-07-28 EP claimed