Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15723770 | 0.76 | KDM5A (0.34) | KDM5A | |
| SCHEMBL24638481 | 0.75 | UCHL1 (0.32) | — | |
| SCHEMBL24638482 | 0.71 | BRAF (0.38) | — | |
| SCHEMBL16751956 | 0.69 | KDM5A (0.39) | KDM5AALDH1A1TSHRHPGDKDM4E | |
| SCHEMBL1581745 | 0.68 | ELANE (0.36) | ALDH1A1KDM4ERECQL | |
| SCHEMBL30730193 | 0.68 | ALDH1A1 (0.34) | KMT2AALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL12993521 | 0.68 | ELANE (0.36) | ALDH1A1KDM4ERECQL | |
| SCHEMBL31489285 | 0.67 | SMN1; SMN2 (0.34) | KDM5ASMN1; SMN2KMT2AALDH1A1HPGD | |
| SCHEMBL28877878 | 0.67 | HDAC8 (0.51) | SMN1; SMN2ALDH1A1TSHRUSP2CYP1A2 | |
| SCHEMBL908831 | 0.66 | HTT (0.36) | SMN1; SMN2ALDH1A1HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022231242-A1 | INDAZOLE COMPOUND HAVING LRRK2 INHIBITORY ACTIVITY | 주식회사 스탠다임 | 2022-11-03 | — | — | WO | disclosed |