SCHEMBL24638481

SCHEMBL24638481

COC(=O)C(C)n1cc(B2OC(C)(C)C(C)(C)O2)c(C#N)n1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UCHL1 P09936 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24638484 0.75 KDM5A (0.36)
SCHEMBL28877860 0.73 SNCA (0.36)
SCHEMBL3663499 0.72 FFAR1 (0.45) UCHL1
SCHEMBL31614199 0.69 UCHL1 (0.35) UCHL1
SCHEMBL31614171 0.68 UCHL1 (0.36) UCHL1
SCHEMBL20193212 0.67
SCHEMBL20360364 0.66 F11 (0.34) UCHL1
SCHEMBL16608637 0.66
SCHEMBL25355674 0.65 CXCR2 (0.33)
SCHEMBL24638482 0.65 BRAF (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022231242-A1 INDAZOLE COMPOUND HAVING LRRK2 INHIBITORY ACTIVITY 주식회사 스탠다임 2022-11-03 WO disclosed